Could a 'Vaginal microbiome Transplant' stop recurring BV?
NCT ID NCT07566754
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether transferring vaginal fluid from healthy donors can help women aged 18-25 with recurrent bacterial vaginosis (BV). Participants first receive standard antibiotics, then the transplant. The goal is to see if this restores a healthy vaginal microbiome and prevents BV from coming back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vaginal microbiome transplantation (VMT) from healthy donors, plus oral metronidazole
What this could lead to
If it works, this could offer a new way to restore healthy vaginal bacteria and reduce repeat infections for women with recurrent bacterial vaginosis.
What could go wrong
This is a small, early-phase trial (75 people) testing a novel biological treatment. It may not work for everyone, and long-term safety and effectiveness are unknown.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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FRESH Clinic
Durban, South Africa
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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