Dentin sensitivity
MONDO:0004059Pain or discomfort caused by exposure of the dentin layer of tooth to thermal, tactile, or other stimuli.
106 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Sealants tested to keep fillings strong and Stain-Free
Disease control CompletedThis study looked at whether adding a surface sealant to a bulk fill dental filling helps it last longer and resist staining. 53 patients received three different fillings each, with or without a sealant. The fillings were checked every 6 months for 5 years to see if they failed,…
Phase: NA • Sponsor: Universidade Federal Fluminense • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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New study tests better fillings for kids with sensitive teeth
Disease control CompletedThis study tested two types of dental overlays in 20 children aged 8-13 with Molar-Incisor Hypomineralisation (MIH), a condition that weakens enamel and causes tooth sensitivity. Each child received one overlay made from a hybrid composite and another from a hybrid ceramic, place…
Phase: NA • Sponsor: Alp Akça • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New scale could help predict fall risk for hospital patients in turkey
Diagnosis CompletedThis study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…
Sponsor: Sisli Hamidiye Etfal Training and Research Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:08 UTC
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Which tooth whitening method causes less pain? new study compares
Symptom relief CompletedThis study tested two ways to whiten teeth: a chemical bleaching gel and a light-activated bleaching gel. Thirty adults with yellowish or brownish stains on their front teeth were randomly assigned to one of the two methods. Researchers measured how white teeth got, how much toot…
Phase: NA • Sponsor: Nahda University • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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New dissolvable strips promise fast relief for sensitive teeth
Symptom relief CompletedThis study tested whether dissolvable mineral-loaded starch strips can quickly relieve dentin hypersensitivity, a common condition causing sharp pain from hot, cold, or touch. 82 adults with sensitive teeth used either the strips or a Novamin toothpaste. The goal was to see if th…
Phase: PHASE4 • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Tooth sensitivity showdown: lasers vs. bee product gel in new study
Symptom relief CompletedThis study tested four approaches for treating dentine hypersensitivity (tooth sensitivity): Nd:YAG laser, diode laser, a herbal propolis-based gel, and a sham (fake) treatment. 140 adults with at least two sensitive teeth were followed for 12 months to see which method reduced p…
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New study tests two ways to soothe sensitive teeth
Symptom relief CompletedThis study tested two treatments for tooth sensitivity: a special varnish and an air-polishing system. Thirty adults with sensitive teeth were treated, and researchers measured pain relief and any tooth color changes. The goal was to find which method works better for easing disc…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:39 UTC
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New gel may soothe sensitive teeth in just 14 days
Symptom relief CompletedThis study tested whether a special tooth gel can help adults with sensitive teeth. Thirty-one participants used the gel three times a day for two weeks. Researchers measured pain from cold air and touch before and after treatment to see if sensitivity improved.
Phase: NA • Sponsor: Lacer S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Toothpaste showdown: can it stop the zing?
Symptom relief CompletedThis study tested whether a desensitizing toothpaste, used alone or with a mouthwash, can reduce tooth sensitivity in adults. 71 participants used the products daily for 14 days. Researchers measured changes in sensitivity to see if the toothpaste worked better than regular tooth…
Phase: NA • Sponsor: Lacer S.A. • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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Laser zaps tooth pain after dental procedure, study finds
Symptom relief CompletedThis study looked at whether using a special laser (diode laser) after a common dental procedure called direct pulp capping can help reduce pain and tooth sensitivity. Fifty-six people with tooth decay that reached the nerve were treated. Half got standard care, and half got stan…
Phase: NA • Sponsor: Hue University of Medicine and Pharmacy • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Shorter gaps between whitening sessions may not increase tooth pain
Symptom relief CompletedThis study tested whether waiting 2 days or 7 days between in-office teeth whitening sessions affects tooth sensitivity. 47 adults with dark teeth received two bleaching sessions using a 35% hydrogen peroxide gel. Their pain levels were recorded for 48 hours after each session, a…
Phase: NA • Sponsor: Universidade Federal Fluminense • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New toothpaste study aims to soothe sensitive teeth
Symptom relief CompletedThis study tested whether a special fluoride toothpaste could better relieve tooth sensitivity compared to a standard fluoride toothpaste. 120 adults with sensitive teeth brushed twice daily for 12 weeks. Researchers measured sensitivity by blowing air on teeth and rating discomf…
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New foam toothpaste promises whiter teeth and less pain
Symptom relief CompletedThis study tested whether a new 2-in-1 foam toothpaste and mouthwash (Scigates) can reduce tooth sensitivity and whiten teeth better than a standard toothpaste. Fifty-seven adults with mild staining and sensitive teeth used either the Scigates product or a control toothpaste thre…
Phase: NA • Sponsor: Prof. Mayyas Al-Remawi • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New toothpaste could soothe sensitive teeth in just weeks
Symptom relief CompletedThis study tested whether a toothpaste with stannous fluoride can reduce tooth sensitivity in 177 Chinese adults aged 18 to 70. Participants brushed twice daily for 8 weeks, and researchers measured pain response to air and touch. The goal was to see if the special toothpaste wor…
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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New toothpaste may stop whitening pain
Symptom relief CompletedThis study tested whether special pastes containing CPP-ACP and fluoride could reduce tooth sensitivity after in-office bleaching. 64 adults received either a paste with CPP-ACP and sodium fluoride, CPP-ACP and stannous fluoride, or a placebo before and after whitening. Pain was …
Phase: NA • Sponsor: Universidade Federal do Para • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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New toothpastes aim to whiten teeth and soothe sensitivity
Symptom relief CompletedThis study tested two experimental toothpastes containing potassium nitrate to see if they can whiten teeth and reduce dentin hypersensitivity (tooth sensitivity). 254 adults with sensitive teeth used one of the toothpastes or a regular fluoride toothpaste for 8 weeks. Researcher…
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Tooth resin treatment soothes sensitive teeth in children
Symptom relief CompletedThis study tested a resin coating on the front teeth of 40 children aged 7-14 who had weak enamel (hypomineralization or hypoplasia) and tooth sensitivity. The treatment aimed to reduce pain from cold air and improve how kids and parents felt about the look and function of their …
Phase: NA • Sponsor: Gizem Tıraşçı • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Warm fillings may reduce tooth sensitivity after cavity repair
Symptom relief CompletedThis study tested whether preheating a special tooth-colored filling material before placing it in cavities helps it last longer and cause less tooth sensitivity. Seventy adults with cavities on both sides of their mouth received one preheated and one non-preheated filling. Over …
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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New tooth-cleaning gadget aims to banish dental drill pain
Symptom relief CompletedThis study tested whether a special ultrasonic handpiece that sprays hydroxyapatite (a natural enamel mineral) can reduce tooth sensitivity during dental cleanings for people with gum disease. Forty adults with moderate to severe periodontitis had half their mouth cleaned with th…
Phase: NA • Sponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Toothpaste showdown: can stannous fluoride beat sensitivity?
Symptom relief CompletedThis completed Phase 3 trial tested whether a toothpaste with stannous fluoride reduces tooth sensitivity better than a potassium-based toothpaste or regular fluoride toothpaste. 123 adults with sensitive teeth used one of the three toothpastes for 7 days. The study measured sens…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New toothpaste aims to soothe sensitive teeth
Symptom relief CompletedThis study tested whether a toothpaste with 5% potassium nitrate can reduce tooth sensitivity better than a regular fluoride toothpaste. 80 adults with sensitive teeth used one of the two toothpastes for eight weeks. The researchers measured sensitivity using a gentle touch and a…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New toothpaste aims to zap tooth pain fast
Symptom relief CompletedThis study tested whether a special toothpaste with 8% arginine (CSPR) can reduce tooth sensitivity better than a regular Colgate toothpaste. 95 adults with sensitive teeth used the toothpaste for 8 weeks. Researchers measured sensitivity using a gentle touch test and a cold air …
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Jambu to the rescue: natural film may soothe whitening pain
Symptom relief CompletedThis study tested a bioadhesive film made from Acmella oleracea (jambu), a plant with natural pain-relieving properties, to reduce tooth sensitivity during teeth whitening. 72 healthy adults received the film, a standard desensitizing gel, or a placebo before bleaching with hydro…
Phase: PHASE3 • Sponsor: Universidade Federal do Para • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New tooth gel could zap sensitivity pain
Symptom relief CompletedThis study tested a new gel-like desensitizer for people with sensitive teeth. 40 adults received either the new polycation-based desensitizer or a standard one. Researchers measured pain relief from touch and cold air. The goal was to see if the new gel safely reduces tooth sens…
Phase: NA • Sponsor: Peking University Hospital of Stomatology • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Laser or toothpaste: which zaps tooth pain best?
Symptom relief CompletedThis study tested two treatments for tooth sensitivity: a special toothpaste with bioactive glass and a low-level laser. 100 adults with sensitive teeth were randomly assigned to one of these treatments or a placebo. The goal was to see which approach provides better and longer-l…
Phase: NA • Sponsor: King Khalid University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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New combo treatment may soothe sensitive teeth pain
Symptom relief CompletedThis study tested whether Gluma, bioactive glass, or a mix of both could reduce tooth sensitivity better than standard fluoride varnish. Forty adults with sensitive teeth were treated and followed for six months. The goal was to see which approach provided the most lasting relief…
Phase: NA • Sponsor: British University In Egypt • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Physiotherapy students test muscle relief techniques on themselves
Symptom relief CompletedThis study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…
Phase: NA • Sponsor: Charles University, Czech Republic • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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New gel may ease tooth sensitivity during whitening treatments
Symptom relief CompletedThis study tested whether a desensitizing gel called UltraEZ can reduce tooth sensitivity during in-office bleaching. Thirty healthy adults with dark teeth received either UltraEZ or a placebo before bleaching. Researchers measured pain levels and color change to see if the gel h…
Phase: EARLY_PHASE1 • Sponsor: University of Santiago de Compostela • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New gel could end the ouch of sensitive teeth
Symptom relief CompletedThis study tested a gel called KH001 to see if it can safely provide long-term relief for sensitive teeth. 120 adults with tooth sensitivity received three applications of the gel or a placebo. Researchers measured pain responses to air and touch to see if the gel worked better t…
Phase: PHASE2 • Sponsor: HysensBio Co., Ltd • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Laser and gel combo zaps tooth pain in new study
Symptom relief CompletedThis study tested whether using a diode laser along with a potassium nitrate gel (a desensitizing toothpaste ingredient) works better than the gel alone for treating sensitive teeth. Twenty-three adults with tooth sensitivity received either the real laser plus gel or a sham lase…
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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New gel could soothe sensitive teeth without the drill
Symptom relief CompletedThis study tested whether a bioactive desensitizer gel can reduce tooth sensitivity better than a standard fluoride varnish. Thirty adults with sensitive teeth received one of the two treatments, and their pain levels were tracked over 6 months. The gel works by releasing calcium…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Can a toothpaste stop the ouch in teeth whitening?
Symptom relief CompletedThis study tested whether a toothpaste with NovaMin (Sensodyne Repair and Protect) can reduce tooth sensitivity during and after teeth bleaching. 90 adults used either the test toothpaste, a standard fluoride toothpaste, or another sensitivity toothpaste. Participants rated their…
Phase: PHASE4 • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New combo treatment offers hope for sensitive teeth after gum therapy
Symptom relief CompletedThis study looked at ways to reduce tooth sensitivity after deep cleaning for gum disease. 48 adults with sensitive teeth received either a desensitizing gel (Gluma), a special laser, or both. Their pain was measured over 6 months. The goal was to see if combining treatments work…
Phase: NA • Sponsor: Trakya University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New toothpaste aims to soothe sensitive teeth in 8-week trial
Symptom relief CompletedThis study tested whether a toothpaste containing 8% arginine can reduce tooth sensitivity better than a regular cavity-protection toothpaste. Eighty adults with sensitive teeth used one of the two toothpastes for eight weeks. The main goal was to measure how much their sensitivi…
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Who should control your sedation during surgery? new study compares options
Symptom relief CompletedThis study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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New toothpaste aims to soothe sensitive teeth
Symptom relief CompletedThis study tested whether a toothpaste containing 8% arginine can reduce tooth sensitivity better than a standard toothpaste. 84 adults with sensitive teeth brushed twice daily for 8 weeks. Researchers measured sensitivity using a gentle touch and a puff of air.
Phase: PHASE3 • Sponsor: Colgate Palmolive • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Toothache after fillings? new study tests a simple solution
Symptom relief CompletedThis study tested whether applying Gluma desensitizer during a filling procedure can reduce immediate tooth sensitivity. 570 adults with cavities in their back molars received either the desensitizer or a standard treatment. The goal was to see if it lowered pain scores right aft…
Phase: NA • Sponsor: Tamil Nadu Dr.M.G.R.Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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New study tests which retainer makes teeth whitening more comfortable
Symptom relief CompletedThis study looked at how satisfied people were with at-home tooth bleaching using two different types of orthodontic retainers. Forty adults who had finished Invisalign treatment used both retainer designs and rated their experience. The goal was to see if one design caused less …
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Which whitening tray do patients prefer? new study compares vivera and essix
Symptom relief CompletedThis study tested how satisfied people are with at-home teeth whitening using two different types of trays: Vivera and Essix. Forty adults with healthy teeth used a 10% carbamide peroxide gel for 2 hours a day, 3 days a week, for 4 weeks with each tray. Researchers measured satis…
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Skip a day, save your smile: new whitening trick cuts sensitivity
Symptom relief CompletedThis study tested whether using a 16% carbamide peroxide whitening gel every other day causes less tooth sensitivity than using it every day. 110 adults with healthy teeth applied the gel for two hours over three weeks. The goal was to see if alternating days reduces pain while s…
Phase: NA • Sponsor: Universidad Rey Juan Carlos • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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New tooth coating could soothe sensitive teeth pain
Symptom relief CompletedThis study tested if a dental adhesive called Single Bond Universal can reduce tooth sensitivity in adults. Fourteen participants with sensitive teeth received either the new coating or a standard desensitizer. They were followed for a year to see which treatment worked better an…
Phase: NA • Sponsor: Peking University Hospital of Stomatology • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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New toothpaste aims to soothe sensitive teeth in seconds
Symptom relief CompletedThis study tested whether a toothpaste and mouthwash made with biomimetic hydroxyapatite could reduce tooth sensitivity in 100 adults with receding gums. Participants had one 30-second application of either the toothpaste or mouthwash in a clinic. Sensitivity was measured before …
Phase: NA • Sponsor: University of Pavia • Aim: Symptom relief
Last updated Jun 26, 2026 18:36 UTC
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New toothpaste could ease tooth pain for millions
Symptom relief CompletedThis study tested whether a toothpaste with calcium sodium phosphosilicate (CSPS) can reduce tooth sensitivity. 217 adults with sensitive teeth used either the CSPS toothpaste or a regular fluoride toothpaste for 8 weeks. Researchers measured how teeth responded to air and touch …
Phase: NA • Sponsor: HALEON • Aim: Symptom relief
Last updated Jun 26, 2026 14:39 UTC
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New turkish health survey could improve care for muscle and joint problems
Knowledge-focused CompletedThis study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…
Sponsor: Istanbul Bilgi University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Dental filling showdown: which technique keeps your fillings intact longer?
Knowledge-focused CompletedThis study tested two ways of placing a flowable bulk fill composite in class II cavities (fillings between back teeth). 38 patients received two fillings each, one with the flowable composite exposed at the edge and one not. Researchers will check for restoration loss, staining,…
Phase: NA • Sponsor: Universidade Federal Fluminense • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New french tool aims to measure the real impact of sensitive teeth
Knowledge-focused CompletedThis study tests a French version of a questionnaire that measures how dentin hypersensitivity (sharp, brief tooth pain) affects people's daily lives. Researchers enrolled 216 adults across three centers in France, including people with different levels of sensitivity and a contr…
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Physios take on ER duty: study tests if they can replace doctors for back pain
Knowledge-focused CompletedThis study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…
Phase: NA • Sponsor: Bern University of Applied Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Tooth enamel defect study probes hidden inflammation in kids
Knowledge-focused CompletedThis study looked at children aged 8 to 13 with a common enamel defect called Molar-Incisor Hypomineralization (MIH). Researchers measured inflammatory markers in the pulp (nerve) of affected teeth and compared them to healthy teeth. The goal was to better understand how MIH affe…
Phase: NA • Sponsor: Marmara University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Can CRPS patients imagine movement? new study investigates
Knowledge-focused CompletedThis completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Mind, spirit, and pain: new study explores what chronic pain patients really believe
Knowledge-focused CompletedThis study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC