Shorter gaps between whitening sessions may not increase tooth pain

NCT ID NCT06394557

Completed Symptom relief Sponsor: Universidade Federal Fluminense Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether waiting 2 days or 7 days between in-office teeth whitening sessions affects tooth sensitivity. 47 adults with dark teeth received two bleaching sessions using a 35% hydrogen peroxide gel. Their pain levels were recorded for 48 hours after each session, and color change was measured after 30 days. The goal was to see if a shorter interval causes more discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 35% Hydrogen Peroxide bleaching gel
What this could lead to: If successful, this could help dentists choose a bleaching schedule that reduces tooth sensitivity while still achieving good whitening results.
What could go wrong: This is a small, completed trial with only 47 participants, so results may not apply to everyone. Tooth sensitivity varies widely between individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOOTH SENSITIVITY

Contacts and locations

Locations

Universidade Federal Fluminense - School of Dentistry

Nova Friburgo, Rio de Janeiro, 28625-650, Brazil

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