New study tests gentler tooth whitening to reduce sensitivity

NCT ID NCT07597044

Ongoing Symptom relief Sponsor: Universidade Federal Fluminense Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different ways of applying a whitening gel to see which causes less tooth sensitivity. Forty adults with darker teeth received two bleaching sessions one week apart. One group had the gel applied for 40 minutes straight, the other for two 20-minute sessions. Researchers measured pain and color change up to 30 days later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: 40% hydrogen peroxide gel (Opalescence Boost)
What this could lead to: If one protocol causes less pain, dentists may adopt it to make whitening more comfortable.
What could go wrong: This is a small, early study with only 40 people, so results may not apply to everyone. Tooth sensitivity is still possible with either method.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TOOTH SENSITIVITY

Contacts and locations

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Locations

Universidade Federal Fluminense - School of Dentistry

Nova Friburgo, Rio de Janeiro, 28625-650, Brazil

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