Jambu to the rescue: natural film may soothe whitening pain

NCT ID NCT07478640

Completed Symptom relief Sponsor: Universidade Federal do Para Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a bioadhesive film made from Acmella oleracea (jambu), a plant with natural pain-relieving properties, to reduce tooth sensitivity during teeth whitening. 72 healthy adults received the film, a standard desensitizing gel, or a placebo before bleaching with hydrogen peroxide. The goal was to see if the jambu film could ease discomfort without affecting whitening results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Acmella oleracea (jambu) extract in a bioadhesive film
What this could lead to: If it works, this could provide a natural, effective way to reduce pain from teeth whitening, making the process more comfortable.
What could go wrong: This is a small, completed Phase 3 trial with 72 participants. The jambu film may not work better than existing desensitizers, and natural products can sometimes cause allergic reactions.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TEETH WHITENING TOOTH SENSITIVITY

Contacts and locations

Locations

Faculdade de Odontologia da Universidade Federal do Pará

Belém, Pará, 66075-110, Brazil

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