Dentin sensitivity

This study tests two kinds of toothpaste that contain hydroxyapatite, a mineral that helps rebuild tooth enamel. Forty children and teens with early signs of enamel damage will brush with one of the pastes twice a day for six months. Researchers will measure if the enamel gets st…

This Phase 3 trial compares three different toothpaste technologies for relieving tooth sensitivity (dentin hypersensitivity). About 132 adults with sensitive teeth will brush with one of three toothpastes: one with 8% arginine, one with 8% arginine plus zinc, or one with 5% calc…

This study tests two different fluoride varnishes to see which one better reduces tooth sensitivity in young adults. Participants receive a single application of either varnish, and researchers measure pain relief and quality of life improvements. The goal is to find a more effec…

This study tests whether a special toothpaste and mousse can reduce tooth sensitivity and enamel damage in adults with celiac disease. Forty participants will either use the toothpaste alone or add a nightly mousse for six months. Researchers will measure changes in sensitivity, …

This study tests whether 3D-printed custom nightguards whiten teeth better and more comfortably than traditional ones. Forty adults with stained teeth will use a standard whitening gel at home. Researchers will measure color change, tooth sensitivity, and gum irritation to find t…

This study looks at whether using a tooth-whitening gel in one long session or several short sessions changes how much tooth pain people feel and how white their teeth get. About 60 adults with darker teeth will receive one of two common whitening gels. Researchers will measure p…

This study looks at tooth wear and tooth sensitivity in 2,500 adults across five U.S. locations. Researchers will use dental scans and questionnaires to find out how common these problems are and what factors—like diet or brushing habits—might cause them. Participants must be 18 …

This study follows 375 adults who recently started experiencing tooth sensitivity and have begun using products to treat it. Over 12 months, researchers will measure changes in oral-health-related quality of life using a questionnaire. The goal is to understand how sensitivity af…