Toothpaste showdown: new study pits three formulas against sensitive teeth
NCT ID NCT07664592
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This Phase 3 trial compares three different toothpaste technologies for relieving tooth sensitivity (dentin hypersensitivity). About 132 adults with sensitive teeth will brush with one of three toothpastes: one with 8% arginine, one with 8% arginine plus zinc, or one with 5% calcium sodium phosphosilicate. Researchers will measure how well each paste reduces pain from air and touch stimuli right after brushing and over two weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- toothpaste containing 8% arginine, 8% arginine with zinc phosphate, or 5% calcium sodium phosphosilicate
- What this could lead to
- If successful, this study could show which toothpaste technology works best for quick and lasting relief from tooth sensitivity.
- What could go wrong
- This is a short-term trial (2 weeks) with only 132 participants, so results may not apply to everyone. Tooth sensitivity can have many causes, and these pastes may not work for all types.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
IEAPOM
RECRUITINGPorto Alegre, Rio Grande do Sul, 91530-001, Brazil
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