Laser or toothpaste: which zaps tooth pain best?
NCT ID NCT07396610
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tested two treatments for tooth sensitivity: a special toothpaste with bioactive glass and a low-level laser. 100 adults with sensitive teeth were randomly assigned to one of these treatments or a placebo. The goal was to see which approach provides better and longer-lasting pain relief over a year.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 60 years * Presence of clinically diagnosed dentinal hypersensitivity in at least one tooth * Positive response to standardized air stimulus test * Good general and oral health Exclusion Criteria: * Presence of dental caries, defective restorations, or cracked teeth in the study tooth * Evidence of pulpal pathology or periapical disease * Periodontal disease requiring active treatment * Use of desensitizing agents or sensitivity treatments within the previous 4 weeks * History of allergy or hypersensitivity to any study materials * Systemic conditions or medications that may affect pain perception * Pregnant or lactating women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sri Rajiv Gandhi College of Dental Sciences & Hospital
Bangalore, India
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Other studies related to the condition(s) this trial covers.