Toothpaste showdown: can stannous fluoride beat sensitivity?
NCT ID NCT06244290
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed Phase 3 trial tested whether a toothpaste with stannous fluoride reduces tooth sensitivity better than a potassium-based toothpaste or regular fluoride toothpaste. 123 adults with sensitive teeth used one of the three toothpastes for 7 days. The study measured sensitivity to touch and air blasts to see which toothpaste worked best.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
stannous fluoride toothpaste
What this could lead to
If it works, this could offer a more effective option for people with sensitive teeth.
What could go wrong
This is a short-term study (7 days) with 123 participants, so results may not apply to long-term use or everyone. Tooth sensitivity can have many causes.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mesa Dental Centre
Costa Mesa, California, 92627, United States