New toothpaste could ease tooth pain for millions

NCT ID NCT06378008

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a toothpaste with calcium sodium phosphosilicate (CSPS) can reduce tooth sensitivity. 217 adults with sensitive teeth used either the CSPS toothpaste or a regular fluoride toothpaste for 8 weeks. Researchers measured how teeth responded to air and touch to see if the special toothpaste helped more than the regular one.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

calcium sodium phosphosilicate toothpaste

What this could lead to

If it works, this could provide a simple, at-home option for people with sensitive teeth to reduce pain from air or touch.

What could go wrong

This is a completed study, but results may not apply to everyone. Tooth sensitivity can have many causes, and the toothpaste may not work for all types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • All Sum Research

    Mississauga, Ontario, L5N 6J2, Canada