New toothpaste aims to soothe sensitive teeth in seconds

NCT ID NCT07057141

Completed Symptom relief Sponsor: University of Pavia Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether a toothpaste and mouthwash made with biomimetic hydroxyapatite could reduce tooth sensitivity in 100 adults with receding gums. Participants had one 30-second application of either the toothpaste or mouthwash in a clinic. Sensitivity was measured before and right after using a standard air test and a pain scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Biomimetic hydroxyapatite toothpaste and mouthwash
What this could lead to: If effective, this could offer a simple, non-invasive way to reduce tooth sensitivity in people with receding gums.
What could go wrong: This is a small, single-application study with no long-term follow-up. Results may not apply to everyday use or to everyone with sensitivity.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity gingival recession

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GINGIVAL RECESSION GENERALIZED MODERATE GINGIVAL RECESSION LOCALIZED MODERATE TOOTH SENSITIVITY

Contacts and locations

Locations

Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia

Pavia, Lombardy, 27100, Italy

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