Pig tendon material could replace painful palate grafts in gum surgery
NCT ID NCT07713199
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This study compares two materials used in gum graft surgery for people with thin or missing gum tissue around teeth or dental implants. One group receives a graft made from their own palate tissue, while the other group receives a graft made from a collagen matrix derived from pig Achilles tendon (Zderm), which is already FDA-approved for this use. The goal is to see if the porcine material works as well as the patient's own tissue in increasing the width of healthy gum tissue. Both materials have been used for years, but this is the first direct comparison.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a porcine-derived collagen soft tissue matrix (Zderm) used as a graft material
- What this could lead to
- If successful, this could show that the porcine collagen matrix works as well as a patient's own tissue for gum grafts, avoiding the need for a second surgical site on the palate.
- What could go wrong
- This is a relatively small study, and the porcine collagen matrix may not perform as well as the patient's own tissue in terms of healing or long-term stability. Individual results may vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Texas Health Science Center at San Antonio School of Dentistry
San Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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