University Hospital, Grenoble

This early-phase study tested whether adding a new drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe for people with locally advanced pancreatic cancer that cannot be removed by surgery. The study involved 43 participants and focused on side effects and how well th…

This study looked at whether a drug called bosentan could lower blood pressure in people with sleep apnea as effectively as the standard treatment, CPAP. Nineteen adults with sleep apnea and mild high blood pressure took part. The goal was to see if blocking a certain chemical in…

This study tested a new, fast, and affordable COVID-19 test called TestNPass. It uses a nose swab to detect the virus and aims to be as accurate as possible. The study involved 400 adults at a hospital in France. The goal was to see if TestNPass can reliably diagnose SARS-CoV-2 i…

This study tested a new, non-invasive imaging technique to measure blood flow in the heart muscle. It involved 36 people with coronary artery disease who already needed a heart catheterization. The goal was to see if the new method could give the same results as the standard inva…

This study tested whether using virtual reality in the waiting room could lower anxiety in 156 adults about to have a heart catheterization. Researchers measured heart rate changes and asked patients about their stress levels. The goal was to see if this simple, drug-free approac…

This study tested whether adding a non-invasive magnetic brain stimulation (rTMS) to standard exercise therapy could reduce pain and improve quality of life in people with fibromyalgia. Forty-two adults with long-term pain participated, receiving either real or placebo rTMS along…

This pilot study tested whether a home-based, supervised exercise program is acceptable and safe for 36 women with anorexia nervosa. Participants completed 8 remote sessions, and researchers measured satisfaction, safety, and changes in weight, self-esteem, and quality of life. T…

This study tested three types of nerve stimulation (two on the brain, one on the spine) to see which works best for easing pain in people with algoneurodystrophy, a chronic pain condition. 36 adults who had pain for over a year and didn't respond to drugs took part. The goal was …

This study followed over 200 sleep apnea patients from a large European database to see what health problems they developed over time, such as heart issues, diabetes, cancers, or death. Researchers also looked at whether using a CPAP machine (the standard treatment) affected thes…

This study looked at whether a weight loss program that includes nutrition and behavior change can reduce the risk of obstructive sleep apnea (OSA) in overweight and obese adults. About 400 participants were observed before and after the program. The goal was to see if weight los…

This study looked at how two conditions that cause muscle spasms in the neck or eyelids affect walking. Researchers measured walking patterns in 40 adults before and after treatment with botulinum toxin. The goal was to understand if the treatment changes how people walk, not jus…

This study looked at why people with chronic inflammatory rheumatism (like rheumatoid arthritis) don't always follow their doctor's recommendations for managing other health problems. Researchers surveyed 229 patients and their doctors to find out what gets in the way. The goal i…

This study tracked nearly 4,800 adults in France who were already in a weight-loss program to see how COVID-19 confinement changed their weight, sleep, and habits. Researchers looked at factors like stress, anxiety, physical activity, and screen time. The goal was to understand h…

This study used brain scans (fMRI) to understand how the hippocampus, a brain area known for memory, also helps with perception. Sixty healthy young adults performed thinking and seeing tasks while their brain activity was measured. The goal was to learn more about how the brain …

This study tested new optical sensors that use light to measure carbon dioxide and oxygen levels in the blood. Twenty healthy adults took part, and the new sensors were compared to standard lab tests. The goal was to see if these sensors work well enough for future use in patient…

This study looked at how the things people say to themselves while running (internal discourses) affect how hard the exercise feels. 76 trail runners ran on a treadmill and rated their effort. The goal was to see if training people to use certain self-talk could make running feel…

This study looked at how the brain processes emotional scenes in healthy younger and older adults. Researchers used functional MRI to compare brain activity when participants judged emotions versus when they identified action tendencies. The goal was to understand how normal agin…

This study tested a new decision tree to help doctors choose the best treatment for acetabular (hip socket) fractures. Researchers looked at 250 patients from a major trauma center to see if the tree improved recovery and reduced the need for hip replacement. The goal was to find…

This study aimed to find early warning signs of obstructive sleep apnea (OSA) in people with Down syndrome, a condition where breathing stops and starts during sleep. Researchers studied 40 adults with Down syndrome using sleep tests and heart monitoring. The goal was to identify…

This study looked at whether taking nitric oxide supplements (like L-Arginine, L-Citrulline, or nitrate) changes how the body responds to exercise. Researchers measured muscle strength and blood flow in 63 healthy, sedentary adults after they took the supplements. The goal was to…

This study tested whether a smartphone app and a wearable activity tracker are practical and acceptable for people with inflammatory rheumatic diseases like rheumatoid arthritis and spondyloarthritis. Over 14 days, 50 participants answered short surveys on their phone and wore a …

This study looked at 825 adults with type 1 diabetes who use an insulin pump to see how many also have obstructive sleep apnea. Sleep apnea is a condition where breathing stops and starts during sleep, and it may be linked to worse diabetes control and complications. The goal was…

This study tested a new questionnaire (NF-scale) designed to quickly assess mood and thinking changes that happen when Parkinson's medication wears off. Researchers worked with 130 French-speaking adults who have Parkinson's and experience motor fluctuations. The goal was to conf…

This study looked at how long-distance trail running (40 to 160 km) affects muscle fatigue, heart function, sleep, and energy balance. Researchers measured muscle strength before and after races in 83 experienced runners. The goal was to better understand the physical stress of t…

This completed French survey studied the burden of on-demand treatment for hereditary angioedema (HAE) attacks from the perspective of 300 patients and their caregivers. It collected information on attack frequency, severity, treatment delays, and impacts on quality of life, soci…

This study looked at how the brain reacts when people exercise in low-oxygen environments, like high altitudes. Thirty healthy men performed exercise while researchers measured brain activity and oxygen levels using special scans and brain stimulation. The goal was to understand …