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New combo shows promise in tough pancreatic cancer trial

NCT ID NCT05546853

First seen Feb 06, 2026 · Last updated May 20, 2026 · Updated 12 times

Summary

This early-phase study tested whether adding a new drug called NP137 to standard chemotherapy (mFOLFIRINOX) is safe for people with locally advanced pancreatic cancer that cannot be removed by surgery. The study involved 43 participants and focused on side effects and how well the tumor responded. The goal was to improve tumor shrinkage and survival without causing too many extra side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AP-HP Pitié Salpetrière

    Paris, 75013, France

  • CHRU Lille

    Lille, 59037, France

  • CHU Poitiers

    Poitiers, 86000, France

  • CHU Rennes

    Rennes, 35033, France

  • CHU St Etienne

    Saint-Etienne, 42055, France

  • CHU de BORDEAUX

    Bordeaux, 33404, France

  • CHU de GRENOBLE ALPES

    Grenoble, Alpes, 38043, France

  • CHU de REIMS

    Reims, 51092, France

  • Hôpital Privé Jean Mermoz

    Lyon, 69008, France

Conditions

Explore the condition pages connected to this study.