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Shock therapy for pain? rTMS shows promise for fibromyalgia

NCT ID NCT01308801

Symptom relief Sponsor: University Hospital, Grenoble Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding a gentle brain stimulation technique called rTMS to standard exercise therapy could reduce pain in people with fibromyalgia. Forty-two adults with long-term pain took part, receiving either real or fake rTMS alongside exercise for 14 weeks. Researchers measured pain levels, quality of life, and mood to see if the combination worked better than exercise alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could offer a non-drug way to ease chronic pain and improve daily life for people with fibromyalgia.
What could go wrong
This is a small, early-stage study with only 42 people. Results may not apply to everyone, and the effect might be modest or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Start date

Apr 2011

Finished

Sep 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * primary fibromyalgia according to the American College of Rheumatology * no contraindication to rehabilitation exercise * pain with VAS \> 4 during at least six months * FIQ score \> 50 * no change in drug therapy over the last month * affiliation to French Health Service Exclusion Criteria: * BMI \> 35kg/m² * patient who has already benefited from rTMS * rTMS contraindication * restless legs symptom * patient suffering from major depression * patient suffering from inflammatory rheumatism, autoimmune disease, other chronic pain pathology * sleep apnea syndrome * no contraindication to rTMS or MRI * pregnant women

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Conditions

The condition(s) this trial relates to.

fibromyalgia Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fibromyalgia

Contacts and locations

Locations

  • CHU de Grenoble

    Grenoble, Isère, 38043, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.