University Hospital, Grenoble

This study tests whether a brain implant can help people who had a stroke regain movement in their arm. Ten participants will first do standard rehab, then get the implant and continue rehab for six months. The goal is to see if the device is safe and helps improve arm function.

This study looks at a new, thinner metal plate used in surgery to fix a common type of ankle fracture. The goal is to see if this plate causes fewer skin problems and less long-term discomfort than standard plates, so patients may not need a second surgery to remove it. About 40 …

This study compares two treatments for heavy bleeding after a miscarriage: a procedure that blocks blood vessels (embolization) alone, or that procedure followed by suctioning of the womb (aspiration). About 110 women will be followed for 12 months to see which approach stops ble…

This study tests a new way to detect prostate cancer early by looking at how suspicious spots on MRI scans change over time, instead of relying on a single scan. The goal is to reduce unnecessary biopsies and avoid treating cancers that are not dangerous. The study will include 3…

This study looks at whether giving a higher dose of the blood thinner enoxaparin can better prevent dangerous blood clots in the legs or lungs of severely injured patients. About 540 adults in intensive care after trauma will receive either the standard or a double dose. The goal…

This study tests whether a gentle, non-invasive brain stimulation technique called tDCS can help manage pain in sedated intensive care patients who cannot speak. The goal is to reduce the need for strong painkillers like morphine, which can have side effects. Researchers will mea…

This study tests whether a stress management program can help adults with myasthenia gravis feel less anxious, depressed, and stressed, and improve their quality of life. About 62 participants will take part in an 8-session program and report their symptoms before and after. The …

This study tests if a gentle, non-invasive electrical current applied to the spine or a nerve bundle can reduce chronic pelvic pain. Sixty adults with pelvic pain for over a year will be randomly assigned to one of two active stimulation groups or a placebo group. The main goal i…

This study looks at whether people with overactive bladder can be monitored at home after receiving botulinum toxin injections, instead of going to the hospital. About 112 participants will be randomly assigned to either home or hospital follow-up. The goal is to see if home moni…

This study tests whether a digital game called LUSHA can help children aged 7-12 with ADHD and their parents. The game aims to motivate behavior change and improve parent-child interaction. Researchers will measure how often families use the app over 3 months and check for any im…

This study looks at whether a special consultation before getting an implantable port (a small device placed under the skin for giving medications) can help cancer patients feel less anxious. About 150 adults who need a port for cancer treatment will be split into two groups: one…

This study aims to find the best way to measure if a supervised exercise program helps people whose advanced lung cancer is stable on treatment. About 63 participants will join a 3-month rehab program. Researchers will check if it improves their strength, ability to stand up from…

This study looks at whether a special imaging technique (LIBS) can detect tiny metal or mineral particles in lung tissue that might be causing chronic lung disease. About 70 adults who already had a lung biopsy will have their stored samples re-analyzed. The goal is to help docto…

This study looks at adults with obstructive sleep apnea whose CPAP therapy isn't working well. It compares treatment decisions made using a home monitoring device (Sunrise) versus those made using a full lab sleep test (polysomnography). The goal is to see if the home device can …

This study will interview 15 adults with stricturing Crohn's disease to learn which symptoms matter most to them and how the condition affects daily life. The goal is to use patient experiences to create a better way for doctors to measure and track the disease. Participants will…

This study looks at whether eating more fiber helps melanoma patients respond better to immunotherapy. Researchers will track the fiber intake of 60 patients and see if those who eat more fiber have less cancer recurrence or progression. The goal is to understand the link between…

This observational study aims to understand why some people with Parkinson's disease experience visual hallucinations. Researchers will compare how prior expectations influence false perceptions during a computer task in patients with and without hallucinations, as well as health…

This study looks at a protein called IL-1RAP found on certain blood cells in people with myelodysplastic syndromes (MDS), a pre-leukemia condition. Researchers want to see if this protein can be targeted by a special immune therapy (CAR-T cells) to kill the diseased cells. They w…

This study tests a new blood test that looks for bacterial DNA in the blood to diagnose brain abscesses. Normally, doctors need surgery to get a sample, but this test might work without it. The study will include 15 adults with brain abscesses and compare the blood test results t…

This study tests a new computer method (HDC) to recognize hand gestures from muscle signals. Ten healthy volunteers will wear a device with 32 sensors on their arm and perform gestures. The goal is to see if the new method is more accurate than existing ones. This research does n…

This study will follow 81 people with early-stage, hormone-positive breast cancer who are at high risk of the cancer coming back. Researchers want to see how often patients stop taking their prescribed CDK4/6 inhibitor pills (abemaciclib or ribociclib) before the full treatment c…

This study looks at 100 kidney transplant patients to understand where the BK virus comes from and why some people get a serious kidney infection. Researchers will compare the virus in the patient and their donor, and check how the immune system responds. The goal is to find bett…

This study will survey current practices around taurolidine lock solutions in 45 patients who have a PICC line for nutrition. The goal is to see if the solution is given correctly according to prescriptions and manufacturer instructions. Researchers will also track any side effec…

This study looks at a new way to control inflammation during flare-ups of Crohn's disease and ulcerative colitis. Researchers will test if tiny oxygen-filled bubbles can reprogram immune cells called monocytes to produce fewer inflammatory signals. The goal is to find a gentler t…

This pilot study will test a new, faster MRI technique called Magnetic Resonance Fingerprinting (MRF) in 10 people who had a stroke within the last 15 days. Standard MRI takes 20-25 minutes, but MRF can capture multiple images in a single, quick sequence. The goal is to see if th…

This study looks at how premature babies learn to match the sounds they hear with the lip movements they see. Researchers will track 60 infants born before 34 weeks to see when this skill develops compared to full-term babies. The goal is to understand why premature children ofte…

This study uses ultrasound to measure how non-invasive ventilation (NIV) changes diaphragm movement in people with ALS. Twenty adults who need NIV will have their diaphragm motion and thickness measured during normal breathing and while using the ventilator. The goal is to see if…

This study aims to translate and validate a French version of the Maternal Satisfaction Scale for Cesarean Section (MSSCS). Researchers will enroll 210 women who had a planned or unplanned cesarean under regional anesthesia. The goal is to provide a reliable tool to measure satis…

This study looks at how immune cells and gut bacteria differ in women with endometriosis compared to those without. Researchers will collect tissue, blood, and stool samples from 40 women having surgery. The goal is to find biological markers that could lead to better treatments,…

This study tests whether measuring jaw movements can accurately assess breathing effort in ICU patients recovering from respiratory failure. Researchers will compare jaw movement signals to the standard invasive method (esophageal pressure) in 50 adults. If successful, this non-i…

This study will use ultrasound to look for medial arterial calcification (hardening of the artery walls) in 60 healthy endurance athletes. The goal is to find out how common this condition is in this group and see if it relates to their training volume and other heart risk factor…

This study tests a new tool that uses famous monuments to see if people with Alzheimer's have more trouble naming and identifying them than healthy older adults. Researchers will compare 220 participants aged 50 and older. The goal is to develop a simple screening test for early …

This study aims to better understand pain in people with arthrogryposis multiplex congenita (AMC) caused by a specific gene change (PIEZO2). Researchers will ask 12 participants aged 10 and older to rate their pain daily for two weeks and fill out questionnaires about quality of …