Monument test may reveal Alzheimer's early
NCT ID NCT07367880
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study explores whether a simple test of naming and identifying famous landmarks can tell apart healthy older adults from those with Alzheimer's disease. Researchers will compare the performance of 220 participants (half with Alzheimer's, half without) on this monument-based task. If successful, the test could become a new screening tool for memory and naming problems.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 220 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Feb 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Participants in the MA group will be selected from among patients attending memory consultations at the CMRR at the CHU Grenoble-Alpes (active file within the department) or from among patients referred to the CMRR by a doctor not practicing at the CMRR (general practitioners or specialists such as neurologists). Healthy elderly participants will be recruited from among those accompanying patients being monitored at the CMRR.
- Ages
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50 to 95 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria : * Alzheimer's disease: * Age ≥ 50 years and older * Possible or probable diagnosis of Alzheimer's disease according to the revised criteria of Mac Khann et al., 2011. * Score 18≤ MMSE ≤26 * Controls: * Age ≥ 50 years and older * MMSE score ≥ 26 For all subjects * No objection from the participant Exclusion criteria * Alzheimer's disease: * Persons referred to in Articles L1121-5 to L1121-8 of the CSP * Controls: * Memory complaints * Persons referred to in Articles L1121-5 to L1121-8 of the CSP For all subjects * Significant neurological or psychiatric history * Taking psychotropic medication (neuroleptics) * Poor command of the French language, comprehension difficulties * Significant hearing or visual impairments (diplopia, nystagmus, scotoma, etc.) * Insufficient exposure to the media and/or socio-cultural knowledge (questionnaire) ; Deficit in face recognition (Benton Face Recognition Test)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Grenoble Alpes
RECRUITINGGrenoble, France
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