Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

This study tests a traditional Chinese herbal medicine called Compound Granules of Hedyotis diffusa in 20 adults with chronic atrophic gastritis, a condition that can lead to stomach cancer. The treatment aims to improve or reverse precancerous changes in the stomach lining. Part…

This study tests a new, less invasive surgery for large chest tumors (teratomas) that are usually removed through a large chest opening. The new method lifts the breastbone with two retractors to create space, allowing doctors to remove the tumor through a small cut below the che…

This study tests a combination of three chemotherapy drugs (thiotepa, busulfan, and fludarabine) given before a stem cell transplant from a half-matched donor. It includes 93 older adults (ages 55-75) with acute myeloid leukemia who are in their first remission. The goal is to se…

This study tests a nasal spray containing exosomes from human stem cells to see if it is safe and helps people recover from a stroke. The trial includes 60 adults who had a stroke within the last 72 hours. Participants receive either the spray or a placebo, and their recovery is …

This study tests whether a combination of two drugs, selinexor and azacitidine, can help prevent NK/T-cell lymphoma from returning after a stem cell transplant. About 39 adults who have already had a transplant will receive this maintenance therapy. The goal is to see if the trea…

This study tests whether a combination of three chemotherapy drugs (thiotepa, cyclophosphamide, and busulfan) given before a stem cell transplant can help people with NK/T-cell lymphoma live longer without their cancer coming back. About 37 adults aged 18 to 70 who are in remissi…

This early study tests a new injection called ART002g1 in 24 adults with a genetic form of high cholesterol (heterozygous familial hypercholesterolemia). The injection uses gene editing to lower a protein that raises cholesterol levels. The main goal is to check safety and how we…

This study tests a higher dose (8 mg) of the drug aflibercept in Chinese patients with polypoidal choroidal vasculopathy (PCV), an eye condition that can cause vision loss. About 174 people will receive three monthly eye injections, then be assigned to one of two follow-up schedu…

This study tests whether adding a third drug, homoharringtonine, to the standard two-drug treatment (venetoclax and azacitidine) can improve remission rates in older adults (ages 60-75) newly diagnosed with acute myeloid leukemia (AML). About 308 participants will be randomly ass…

This study looks at 84 people with T-cell acute lymphoblastic leukemia or lymphoma who are in their first complete remission after chemotherapy. Researchers want to see if using the patient's own stem cells or a donor's stem cells works better to keep the cancer from coming back.…

This study looks at whether a special surgery (electrocautery) followed by heated chemotherapy given directly into the chest can help people with thymic tumors that have spread to the lining of the chest. About 70 adults aged 16 to 80 will take part. The goal is to see if this co…

This study tests whether a ginkgo biloba extract (EGb761) can help control diabetic retinopathy, an eye disease caused by diabetes. About 200 adults with long-term diabetes will take either the ginkgo pill or standard treatment for 2 years. Researchers will measure changes in eye…

This study tests whether special glasses with a dynamic optical film can slow the growth of the eye in children aged 6 to 10 with low hyperopia (farsightedness). 180 children will be split into two groups: one group wears the special glasses, and the other group receives no activ…

This study compares 6 versus 3 cycles of chemotherapy given before surgery for people with a rare type of thymus gland tumor (thymoma or thymic carcinoma) that has spread locally but may still be removable. About 116 adults aged 18-65 will be randomly assigned to one of two treat…

This study looks at whether adding a constipation capsule (Shouhui Tongbian) to standard pancreatic enzyme pills can improve digestion in people who had part of their pancreas removed due to cancer. About 80 adults will take the combination for 12 weeks. The goal is to see if it …

This early-phase study tests a new drug (BRP-020063) that first helps doctors see tumors on a PET scan, then delivers a low dose of radiation to treat them. It enrolls 10 adults with advanced metastatic solid tumors, mainly urothelial carcinoma. The goal is to check safety, how t…

This study tests a new navigation system that combines PSMA-PET, MRI, and ultrasound images to guide surgeons during robot-assisted prostate removal. About 98 men with prostate cancer that has spread just outside the gland will take part. The goal is to remove all cancer while pr…

This study tests whether using a special LED red light device, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be split into four groups: three groups use the red light for different l…

This study looks at whether a new blood test can help doctors diagnose hemolytic disease of the newborn (HDN) earlier. Researchers will test leftover blood samples from 100 pregnant women who are at high risk for this condition. The goal is to see if the test can predict which ba…

This study tests whether letting cataract patients watch a virtual reality simulation of their upcoming surgery can reduce anxiety during the real procedure. About 60 adults scheduled for cataract surgery will wear VR glasses beforehand to see and hear what happens in the operati…

This study tests a new way to give pelvic radiation to cervical cancer patients who already have hemorrhoids. The goal is to see if protecting the anal canal from radiation can reduce symptoms like pain, bleeding, and discomfort. About 300 patients will be randomly assigned to ei…

This study compares two ways to remove kidney stones: a new super pulse laser with a special suction sheath versus a standard laser with a regular sheath. About 140 adults with kidney or ureter stones will take part. The goal is to see which method clears more stones and causes f…

This study compares two ways to clean chronic skin wounds: using a surgical microscope or just the naked eye. About 98 adults with wounds from injuries, diabetes, or pressure sores will take part. The goal is to see which method leads to faster healing, less pain, and better drai…

This study tests an artificial intelligence system called QiLin that helps doctors decide when to give anti-VEGF injections for retinal diseases like wet age-related macular degeneration, diabetic macular edema, and retinal vein occlusion. About 200 patients who have completed in…

This study will look back at medical records of 500 Chinese adults with type 1 diabetes to see if adding glucose-lowering pills to their insulin helps control blood sugar better than insulin alone. The goal is to understand real-world effects and safety over time. No new treatmen…

This study aims to find out if changes in specific immune cells in the blood can predict how well chemoimmunotherapy works in people with advanced non-small cell lung cancer. Researchers will collect blood samples from 80 participants before and after two treatment cycles. The go…

This study looks at whether depression and asthma are related, and if one might cause the other. Researchers will review medical records from 500 adults and use genetic data to find links. The goal is to understand the connection better, not to test a new treatment.

This study looks at why people living in hot, humid places are more likely to get kidney stones. Researchers will compare gut bacteria and certain blood chemicals between 270 kidney stone patients and healthy people. They hope to find links between environment, gut health, and st…