Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

This study looks at people with peripheral T-cell lymphoma whose cancer went away after their first treatment. It compares two options: getting a stem cell transplant using their own cells, or simply watching and waiting. The goal is to see which approach helps keep the cancer aw…

This early-stage trial tests a new treatment for adults with acute myeloid leukemia (AML) that has come back or not responded to standard therapy. The treatment uses specially engineered immune cells (CLL-1 CAR-NK cells) designed to find and attack leukemia cells. The main goals …

This study tests whether two drugs, cidabenamine and azacitidine, can keep high-risk peripheral T-cell lymphoma from returning after a stem cell transplant. About 40 adults aged 18 to 70 will receive this maintenance therapy. The goal is to see if the combination improves surviva…

This study is for people with peripheral T-cell lymphoma whose cancer did not shrink or got worse after standard chemotherapy. It compares two approaches: a donor stem cell transplant (allogeneic HSCT) or other rescue treatments. The goal is to see which option helps patients liv…

This study tests whether taking krill oil supplements daily for 3 months can reduce drusen (fatty deposits) in the eyes of people with early or intermediate dry age-related macular degeneration (AMD). 24 adults will receive either krill oil or a placebo. The goal is to see if kri…

This early-stage study tests a gene therapy called LX111 for diabetic macular edema, a condition that causes vision loss due to swelling in the eye. About 32 adults with diabetes will receive a single injection into the eye. The goal is to see if it is safe and can reduce swellin…

This study looks at two types of stem cell transplants for people with a rare blood cancer called peripheral T-cell lymphoma that only partially improved after initial treatment. One group receives their own stem cells, while the other gets stem cells from a healthy donor. The go…

This study tests whether a daily pill called golidocitinib can help keep peripheral T-cell lymphoma from coming back after successful first chemotherapy. About 136 adults who responded to initial treatment but cannot have a stem cell transplant will receive either the study drug …

This study tests whether a non-invasive brain stimulation technique called rTMS can improve deep sleep and slow the progression of Parkinson's disease. Researchers will enroll 56 adults aged 50-80 with mild to moderate Parkinson's. The approach uses magnetic pulses to enhance slo…

This study tests whether adding a new oral drug (ivarmacitinib) to standard medications can prevent acute graft-versus-host disease (GVHD) in 82 adults receiving a stem cell transplant from a female donor who has given birth. GVHD is a serious complication where donor cells attac…

This early study tests a single injection of LX111 gene therapy in 10 people aged 50 or older with wet age-related macular degeneration (nAMD). The goal is to see if it is safe and can help control the disease, possibly reducing the need for frequent eye injections. Participants …

This study looks at whether people at low risk of infection can safely skip antibiotics before a common kidney stone removal procedure. About 500 adults aged 18-75 with small kidney stones will be randomly assigned to receive either the usual single dose of antibiotics or no anti…

This early-phase trial tests a personalized cell therapy for people with a specific type of lymphoma linked to the Epstein-Barr virus (EBV). The treatment uses the patient's own immune cells, modified to recognize and attack EBV-infected cancer cells. The study aims to find a saf…

This early-phase study tests whether immune cells from the original donor, combined with a low dose of interleukin-2, can safely treat chronic graft-versus-host disease (cGVHD) that hasn't responded to standard steroids. About 18 adults aged 18-70 who had a stem cell transplant a…

This study looks at how well the drug adebrelimab works and how safe it is for people with advanced small cell lung cancer in real-world settings. Researchers will track side effects and survival times in 500 patients. The goal is to see if this treatment helps control the diseas…

This study tests whether adding targeted local therapy to standard hormone treatment can delay disease progression in men with metastatic hormone-sensitive prostate cancer. Participants first receive hormone therapy for 8 months, then those with remaining active tumors seen on a …

This study tests a new combination of three drugs (venetoclax, azacitidine, and homoharringtonine) followed by a stem cell transplant for people with intermediate or high-risk acute myeloid leukemia (AML). About 56 adults aged 18-55 who have not had prior leukemia treatment will …

This early-phase study tests a gene therapy called LX107 for people with a rare inherited eye disease that causes vision loss. The treatment is given as an injection under the retina and aims to improve vision and slow disease progression. The study will enroll 13 adults and chil…

This study compares two types of lasers used to break up kidney stones during a procedure called ureteroscopy. About 136 adults aged 18–70 with kidney stones will be randomly assigned to receive either the new superpulse thulium fiber laser or the standard holmium laser. The goal…

This study tests whether an app that collects patient-reported data (like pain, appetite, and weight) combined with artificial intelligence can better assess nutritional needs and improve recovery after pancreatic cancer surgery. Researchers will enroll 200 adults aged 18-80 who …