Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

This study is observing how well the drug adebrelimab works and how safe it is for people with advanced small cell lung cancer in real-world treatment settings. It will follow 500 patients who are already receiving or eligible for this treatment, tracking their survival, disease …

This early-stage study is testing a single gene therapy injection, called LX111, for people with wet age-related macular degeneration (AMD), a leading cause of vision loss. The main goal is to see if this one-time treatment is safe and if it can help control the disease, potentia…

This early-stage study is testing whether a special type of donor immune cell, called a Treg cell, given along with a protein called interleukin-2, can help control chronic graft-versus-host disease (cGVHD) in patients who haven't responded well to standard steroid treatments. Th…

This study is testing whether a stem cell transplant helps keep T cell lymphoma from coming back better than simply watching patients who are already in remission. Researchers will compare two groups: one that receives their own stem cells back after high-dose chemotherapy, and a…

This study is testing whether a pill called golidocitinib can help keep cancer from coming back in people with peripheral T-cell lymphoma who responded well to their first chemotherapy. It compares the drug to a placebo (sugar pill) in 136 patients who are not getting a stem cell…

This study is testing a multi-step treatment for adults with newly diagnosed, higher-risk acute myeloid leukemia (AML). The goal is to use a combination of chemotherapy drugs to put the cancer into deep remission, followed by a stem cell transplant from a donor to try to keep it …

This early-stage study is testing a personalized cell therapy for patients with EBV-positive lymphoma that has returned or not responded to standard treatments. Researchers will collect a patient's own immune cells, modify them in a lab to better target the Epstein-Barr virus (EB…

This study is testing a smartphone app that uses artificial intelligence to monitor patients' nutrition and health after surgery for pancreatic cancer. It will track things like weight, appetite, and strength to help spot nutritional problems early. The goal is to see if this AI …

This study is testing if adding targeted radiation to standard hormone therapy helps control advanced prostate cancer for a longer time. It will include about 192 men newly diagnosed with prostate cancer that has spread. After initial hormone therapy, doctors will use a special s…

This study is testing whether a combination of two drugs, Cidabenamine and Azacitidine, can help prevent cancer from returning in people with high-risk T-cell lymphoma who have already received a stem cell transplant from a donor. The goal is to see if this 'maintenance' therapy …

This study is testing a newer laser (superpulse thulium fiber laser) against the current standard laser (holmium) for breaking up kidney stones. Doctors will compare how well each laser clears stones, how long the procedure takes, and how safe it is for patients. The goal is to f…

This study is testing if a non-invasive brain stimulation technique called rTMS can slow the progression of Parkinson's disease. Researchers believe improving a patient's deep, slow-wave sleep might protect the brain. The study will measure changes in movement, balance, sleep qua…

This study aims to find out which of two stem cell transplant procedures works better for patients with a type of blood cancer called peripheral T-cell lymphoma. The cancer must have partially responded to the first round of treatment. Researchers will compare transplants using a…

This early-stage study is testing a new gene therapy called LX111 for diabetic macular edema, a vision-threatening complication of diabetes. Researchers will give a single injection into the eye to 32 participants who have previously responded to standard anti-VEGF treatments. Th…

This early-stage study is testing a new gene therapy called LX107 for people with a rare inherited eye disease that causes vision loss. Doctors will inject the therapy directly into the retina of one eye in up to 13 patients to see if it is safe and if it can improve or stabilize…

This early-stage trial is testing the safety and initial effectiveness of a new cell therapy called CLL-1 CAR-NK for adults with acute myeloid leukemia (AML) that has returned or not responded to standard treatments. The study will give the modified immune cells to about 24 parti…

This study is testing whether taking krill oil supplements for three months can help control dry age-related macular degeneration (AMD), a common cause of vision loss in older adults. Researchers will compare krill oil to a placebo in 24 participants with early or intermediate dr…