New laser may zap kidney stones faster and safer

NCT ID NCT06667557

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares two types of lasers used to break up kidney stones during a minimally invasive procedure called ureteroscopy. One laser uses a superpulse thulium fiber (sTFL), the other is a standard holmium laser. Researchers will enroll 136 adults aged 18–70 with kidney stones 6–20 mm in size. The main goal is to see which laser clears more stones after 3 months, and which causes fewer complications or shorter surgery times.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Superpulse thulium fiber laser (sTFL) and holmium:YAG laser (Ho:YAG) — both used as surgical devices to break up kidney stones during ureteroscopy.

What this could lead to

If sTFL proves better, it could become the preferred laser for kidney stone surgery, offering higher stone clearance and fewer complications.

What could go wrong

This is a relatively small trial (136 people) comparing two established techniques. Even if sTFL shows advantages, the difference may be modest and not change practice widely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis ureterolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai General Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 201620, China

    Contact Phone: •••-•••-••••