Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

This study tests how well and how safe fluticasone propionate nebulized suspension works in babies aged 0 to 24 months with acute wheezing. It compares fluticasone to budesonide, another commonly used inhaled steroid. About 240 babies will be randomly assigned to receive either f…

This study looks at two stem cell transplant methods—using a patient's own cells or a donor's cells—as a follow-up treatment for people with T-cell acute lymphoblastic leukemia or lymphoma who are in their first complete remission. The goal is to see which approach better prevent…

This study tests whether a combination of three chemotherapy drugs (thiotepa, busulfan, and fludarabine) given before a stem cell transplant can help older adults with acute myeloid leukemia stay in remission longer. About 93 patients aged 55 to 75 who are in their first remissio…

This study looks at whether adding Shouhui Tongbian capsules to standard pancreatic enzyme therapy can help people digest food better after surgery for pancreatic cancer. About 80 adults who had a Whipple procedure and have digestive issues or constipation will take part. The mai…

This Phase 3 trial will test whether adding homoharringtonine to the standard two-drug regimen of venetoclax and azacitidine improves remission rates in adults aged 60-75 with newly diagnosed acute myeloid leukemia (AML). About 308 participants will be randomly assigned to receiv…

This early study tests a new injection called ART002g1 in 24 adults with a genetic form of high cholesterol (HeFH). The injection uses gene editing to lower a protein that raises cholesterol levels. The main goal is to check safety and how well the drug works at reducing choleste…

This study tests whether 6 cycles of chemotherapy before surgery is better than 3 cycles for people with a rare type of thymus gland tumor. About 116 adults with locally advanced but removable tumors will be randomly assigned to one of the two treatment groups. The goal is to see…

This early-stage trial tests a nasal spray made from human stem cell exosomes in 60 people who recently had a stroke. The spray is given once or daily for 14 days, alongside standard care. The main goal is to see if it is safe, and researchers will also check if it helps improve …

This study looks at whether combining a special surgery (electrocautery) with heated chemotherapy given directly into the chest can help people with thymic tumors that have spread to the chest lining. About 70 participants will receive the treatment and be followed for up to 3 ye…

This study tests a traditional Chinese herbal formula (Compound Granules of Hedyotis diffusa) in 20 adults with chronic atrophic gastritis, a condition that can lead to stomach cancer. Participants take the herbal granules for 12 months and are followed for another 12 months. The…

This study tests a stronger dose (8 mg) of the drug aflibercept in Chinese patients with polypoidal choroidal vasculopathy (PCV), a type of wet age-related macular degeneration that can cause rapid vision loss. About 174 people who have not been treated before will receive three …

This trial tests a new way to remove kidney stones using a special laser and a flexible suction sheath. 140 adults with stones between 6mm and 20mm will be randomly assigned to get the new suction sheath or a standard sheath. The goal is to see if the new method clears more stone…

This study tests if using a special LED red light device twice a day, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be randomly assigned to different groups to find the best treatmen…

This trial tests a new imaging system that combines PSMA-PET, MRI, and ultrasound to guide robot-assisted prostate surgery. The goal is to help surgeons remove all cancer while sparing healthy tissue, nerves, and urinary control. About 98 men with prostate cancer will take part t…

This study tests a combination of three chemotherapy drugs (thiotepa, cyclophosphamide, and busulfan) given before a stem cell transplant for people with NK/T-cell lymphoma. The goal is to see if this approach helps keep the cancer from coming back. About 37 adults aged 18-70 who…

This study tests whether a combination of two drugs, selinexor and azacitidine, can help prevent NK/T-cell lymphoma from returning after a stem cell transplant. About 39 adults aged 18-70 who have already received a transplant will take these drugs as maintenance therapy. The goa…

This study tests whether a ginkgo biloba extract (EGb761) can slow or prevent diabetic retinopathy, an eye disease caused by diabetes. About 200 adults with long-standing diabetes will take either ginkgo or standard treatment for 2 years. Researchers will measure changes in eye b…

This trial tests an artificial intelligence system called QiLin that helps doctors decide when to give anti-VEGF injections for retinal diseases like wet AMD, DME, and RVO. About 200 patients who have completed initial treatment will be randomly assigned to have their doctor use …

This study looks at whether measuring bleeding between mother and baby can help diagnose hemolytic disease of the newborn (HDN), a condition where the mother's antibodies attack the baby's red blood cells. Researchers will test leftover blood samples from 100 pregnant women at hi…

This study tests a special optical film called S.T.O.P®KIT that attaches to eyeglasses. The goal is to slow down the growth of the eye in children aged 6 to 10 with mild farsightedness, which may help prevent nearsightedness later. 180 children will be split into two groups: one …

This study tests whether a newer painkiller, tegileridine, can control pain after major laparoscopic abdominal surgery as well as the standard drug sufentanil, but with fewer gastrointestinal side effects like nausea or constipation. About 84 adults having elective major abdomina…

This study tests whether letting cataract surgery patients watch a virtual reality (VR) simulation of the procedure beforehand can reduce their anxiety during the real surgery. About 260 adults scheduled for cataract surgery will either use VR glasses to experience the sights and…

This study tests whether letting cataract surgery patients watch a virtual reality (VR) simulation of the procedure beforehand can reduce their anxiety during the actual surgery. Sixty adults scheduled for cataract surgery will either watch the VR video or receive standard care. …

This study compares two ways of cleaning chronic skin wounds: using a surgical microscope versus just the naked eye. About 98 adults with wounds from diabetes, pressure, or injury will be randomly assigned to one method. Researchers will measure wound healing, pain, and drainage …

This trial tests a new surgical method for removing large chest tumors (teratomas) without opening the chest. Instead, surgeons use a small cut below the breastbone and a special retractor to lift the sternum, creating space to work. The goal is to see if this approach reduces pa…

This trial tests whether protecting the anal canal during pelvic radiation can reduce hemorrhoid-related symptoms like pain, bleeding, and discomfort in cervical cancer patients. 300 women who had a hysterectomy and need radiation will be randomly assigned to standard radiation o…

This study will look back at medical records of 500 Chinese adults with type 1 diabetes to see if adding glucose-lowering pills to insulin helps control blood sugar better than insulin alone. The main goal is to check changes in HbA1c (average blood sugar over 2-3 months) and how…

This study aims to see if changes in certain immune cells in the blood can predict how well advanced lung cancer patients respond to a combination of chemotherapy and immunotherapy. About 80 adults with stage IIIB or IV non-small cell lung cancer will give blood samples before an…

This study will analyze data from 500 adults to see if depression and asthma are connected, and if one might cause the other. Researchers will use medical records and genetic information to identify factors like age, smoking, or weight that could influence the link. No new treatm…

This study will compare gut bacteria and blood markers between 270 kidney stone patients and healthy people in Shanghai. Researchers want to see if hot, humid weather changes gut microbes and tryptophan metabolism in ways that promote stone formation. No treatment is given; the g…