Shanghai General Hospital, Shanghai Jiao Tong University School Of Medicine

This study looks at whether adding Shouhui Tongbian capsules to standard pancreatic enzyme pills can help people who had part of their pancreas removed due to cancer. About 80 adults who have digestive problems or constipation after surgery will take the combination for 12 weeks.…

This study tests whether a ginkgo biloba extract (EGb761) can slow or prevent diabetic retinopathy, a common eye complication of diabetes. Researchers will enroll 200 adults with long-standing diabetes and mild to moderate eye changes. Participants will either take the ginkgo sup…

This study looks at whether a combination of surgery to remove tumor spots from the chest lining followed by heated chemotherapy can help people with a rare thymus gland tumor that has spread. About 70 adults aged 16 to 80 will take part. The goal is to see if this approach delay…

This study tests a new navigation system that combines PSMA-PET, MRI, and ultrasound images to guide surgeons during robot-assisted prostate removal. About 98 men with prostate cancer that has spread just outside the gland will take part. The goal is to remove all cancer while pr…

This study tests whether two drugs, selinexor and azacitidine, can safely prevent NK/T-cell lymphoma from returning after a stem cell transplant. About 39 adults who have already had a transplant will take these drugs as maintenance therapy. The goal is to see if this approach im…

This early study tests a single injection of ART002g1 in 24 adults with inherited high cholesterol (HeFH) who need lower LDL levels. The injection uses gene editing to turn off a liver gene (PCSK9) that raises cholesterol. The main goal is to check safety and how well it lowers c…

This early-phase study tests a new drug called BRP-020063 in 10 people with advanced solid tumors that have spread. The drug is used first for imaging to find tumors, then a low dose is given to see if it can treat them. The main goal is to check safety and how the drug moves thr…

This study tests whether special glasses with a unique optical film can slow the natural lengthening of the eye in children aged 6 to 10 with mild farsightedness. 180 children will either wear these glasses or receive standard care for one year. The goal is to see if the glasses …

This study tests a specific chemotherapy combination (thiotepa, busulfan, and fludarabine) given before a stem cell transplant from a half-matched donor. It includes 93 older adults (ages 55-75) with acute myeloid leukemia in first remission. The goal is to see if this approach c…

This study tests whether a nasal spray made from human stem cell exosomes is safe and can help people recover after a stroke. It involves 60 adults with mild to moderate stroke who will receive the spray or a placebo. The goal is to see if the spray improves brain function and re…

This study tests a combination of three chemotherapy drugs (thiotepa, cyclophosphamide, and busulfan) given before a stem cell transplant for people with NK/T-cell lymphoma. The goal is to see if this approach helps keep the cancer from coming back and improves survival. About 37…

This study tests a new, less invasive surgery for people with large chest tumors (teratomas). Instead of opening the chest, surgeons lift the breastbone with a special device to create space and remove the tumor through a small cut below the breastbone. The goal is to reduce pain…

This study compares two different lengths of chemotherapy before surgery for people with a rare type of chest tumor (thymoma or thymic carcinoma). About 116 adults aged 18 to 65 with advanced but removable tumors will receive either 6 or 3 cycles of chemo, then have surgery. The …

This study looks at 84 people with T-cell acute lymphoblastic leukemia or lymphoma who are in their first complete remission after chemotherapy. Researchers want to see if using the patient's own stem cells (autologous) or a donor's stem cells (allogeneic) leads to better outcome…

This study tests a traditional Chinese herbal formula (Compound Granules of Hedyotis diffusa) in 20 adults with chronic atrophic gastritis, a condition that can lead to stomach cancer. The goal is to see if the herbs can improve stomach lining damage and reduce cancer risk. Parti…

This study tests a higher dose (8 mg) of the drug aflibercept in Chinese patients with polypoidal choroidal vasculopathy (PCV), a condition that causes vision loss. About 174 people will receive three initial monthly eye injections, then be split into two groups: one gets additio…

This phase 3 trial tests whether adding homoharringtonine to the standard two-drug regimen (venetoclax and azacitidine) improves remission rates in adults aged 60-75 with newly diagnosed acute myeloid leukemia (AML). About 308 participants will be randomly assigned to receive eit…

This study tests whether using a special LED red light device, along with glasses that have defocus lenses, can slow the progression of nearsightedness (myopia) in children aged 6 to 14. About 364 kids will be split into four groups: three groups use the red light for different l…

This study is testing a new way to diagnose hemolytic disease of the newborn (HDN) using a blood test that measures bleeding between mother and baby. Researchers will follow 100 pregnant women at high risk for HDN to see if this test can spot the condition more accurately. The go…

This study tests whether letting cataract surgery patients watch a virtual reality (VR) simulation of the procedure beforehand can reduce their anxiety during the real surgery. Sixty participants will wear VR glasses to see and hear what happens during the operation. The goal is …

This study tests whether using a surgical microscope to clean skin wounds leads to better healing than cleaning them with the naked eye. About 98 adults with chronic wounds from diabetes, injuries, or pressure sores will take part. Researchers will measure wound healing, pain, an…

This study compares two ways to remove kidney stones: a new super pulse laser with a special suction sheath versus the same laser with a standard sheath. About 140 adults with stones between 6 and 20 mm will take part. The goal is to see if the new suction method clears more ston…

This study tests a new way to give pelvic radiation after cervical cancer surgery that protects the anal canal. The goal is to reduce painful hemorrhoid symptoms like bleeding and burning during treatment. About 300 patients with hemorrhoids will be randomly assigned to either st…

This study looks back at medical records of 500 Chinese adults with type 1 diabetes to see if adding glucose-lowering pills to their insulin helps control blood sugar better than insulin alone. The main goal is to compare average blood sugar levels (HbA1c) between the two groups …

This study looks at how hot and humid environments might increase the risk of kidney stones by changing the bacteria in your gut and how your body processes certain nutrients. Researchers will compare stool and blood samples from 270 people—some with kidney stones and some withou…

This study tests an AI system called FM-VEGF-CDSS that helps doctors decide the best time for anti-VEGF eye injections in people with wet age-related macular degeneration, diabetic macular edema, or retinal vein occlusion. The AI looks at eye scans and medical records to suggest …

This study looks at 500 adults to see if depression and asthma are related and if one causes the other. Researchers will review medical records and use genetic data to find connections. No new treatments are tested; the goal is to better understand how these conditions interact.

This study looks at whether changes in certain immune cells in the blood can help predict how well chemotherapy combined with immunotherapy works for people with advanced non-small cell lung cancer. Researchers will take blood samples before and after the first two treatment cycl…