New painkiller aims to ease Post-Surgery pain without stomach upset
NCT ID NCT07637968
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a newer painkiller, tegileridine, can control pain after major laparoscopic abdominal surgery as well as the standard drug sufentanil, but with fewer gastrointestinal side effects like nausea or constipation. About 84 adults having elective major abdominal surgery will receive one of the two drugs through a patient-controlled pump after surgery. The main goal is to see if tegileridine provides better gut tolerance while keeping pain scores low.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Tegileridine
What this could lead to
If tegileridine works as hoped, it could offer a painkiller option after abdominal surgery that is gentler on the stomach and bowels while still controlling pain effectively.
What could go wrong
This is a small, early-phase trial (84 people) comparing two drugs, so results may not apply to everyone. Tegileridine might not prove better or could have unexpected side effects.
Disclaimer
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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