New hope for PCV: higher-dose eye injection may reduce treatment burden
NCT ID NCT07365371
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a stronger dose (8 mg) of the drug aflibercept in Chinese patients with polypoidal choroidal vasculopathy (PCV), a type of wet age-related macular degeneration that can cause rapid vision loss. About 174 people who have not been treated before will receive three monthly eye injections, then be assigned to one of two retreatment schedules based on disease activity. The goal is to see if the higher dose can improve vision and keep the disease under control with fewer visits and injections over one year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Affiliated Eye Hospital of Nanchang University
Nanchang, Jiangxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Affiliated Hospital Of Shandong Second Medical University
Weifang, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Hospital
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Beijing Tongren Hospital, CMU
Beijing, Beijing Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Eye & ENT Hospital of Fudan University
Shanghai, Shanghai Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiangsu Province Hospital , The First Affiliated Hospital with Nanjing Medical University
Nanjing, Jiangsu, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Jiaxing Hospital of T.C.M
Jiaxing, Zhejiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Renmin Hospital Of Wuhan University
Wuhan, Hubei, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shandong Provincial Hospital
Jinan, Shandong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, China
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Shanxi Eye Hospital
Taiyuan, Shanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital Of Harbin Medical University
Harbin, Heilongjiang, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The First Affiliated Hospital of Kunming Medical University
Kunming, Yunan, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
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The First People's Hospital Of Xianyang
Xianyang, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
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The Second Norman Bethune Hospital Of Jilin University
Jilin City, Jilin, China
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The Second People's Hospital Of Foshan
Foshan, Guangdong, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tianjin Eye Hospital
Tianjin, Tianjin Municipality, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Xi' AN No.1 Hospital
Xi'an, Shaanxi, China
Contact Phone: •••-•••-•••• Email: •••••@•••••