Heated chemo after surgery shows promise for rare chest cancer spread
NCT ID NCT07328074
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether combining a special surgery (electrocautery) with heated chemotherapy given directly into the chest can help people with thymic tumors that have spread to the chest lining. About 70 participants will receive the treatment and be followed for up to 3 years to see if it delays the cancer's return and improves quality of life. The approach aims to destroy remaining cancer cells with heat and drugs, but it is still experimental and carries risks from both surgery and chemotherapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cisplatin and doxorubicin (heated chemotherapy)
- What this could lead to
- If this works, it could offer a more effective way to control thymic tumors that have spread to the chest lining, potentially delaying recurrence and improving survival.
- What could go wrong
- This is a small, early observational study with no comparison group, so results may not be definitive. The heated chemotherapy can cause serious side effects, and the surgery carries risks like infection or bleeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Shanghai General Hospital, Department of Thoracic Surgery
Shanghai, Shanghai Municipality, 200080, China
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Other studies related to the condition(s) this trial covers.
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