Ohio State University
Clinical trials sponsored by Ohio State University, explained in plain language.
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New program aims to help medicaid patients eat better and control chronic disease
Disease control CompletedThis study tested a 24-week program for 106 Medicaid members with stage 2 cardiovascular-kidney-metabolic syndrome. The program offered food support, nutrition counseling, and help with social needs. Researchers wanted to see if people would stick with the program and if it impro…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 26, 2026 02:54 UTC
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Double jeopardy: new program tackles stress and hypertension in black dementia caregivers
Disease control CompletedThis pilot study tested a lifestyle program for African American women who care for a family member with Alzheimer's or related dementia and also have high blood pressure. The program focused on stress management, healthy eating, and physical activity to help lower blood pressure…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 26, 2026 02:46 UTC
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Milk membrane may tame gut inflammation in metabolic syndrome
Disease control CompletedThis study tested whether a milk ingredient called milk fat globule membrane (MFGM) can reduce harmful substances from the gut that contribute to metabolic syndrome. 30 adults with metabolic syndrome followed a controlled diet with either MFGM-enriched milk or a placebo milk for …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Teens help teens get moving in appalachian study
Disease control CompletedThis study tested a program where trained peer mentors (older students) helped 9th and 10th graders in Appalachian high schools become more physically active. The program was compared to a teacher-led version. The goal was to see if peer support could improve health behaviors lik…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Green tea extract shows promise for gut health in metabolic syndrome
Disease control CompletedThis study looked at whether green tea extract can improve gut health and lower inflammation in people with metabolic syndrome and in healthy adults. 46 participants took either green tea extract or a placebo for one month, then switched to the other for another month. The resear…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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Housing first: a bold experiment to stop opioid addiction before it starts
Prevention CompletedThis study tested whether giving homeless young people (ages 18-24) a place to live along with support services could prevent them from developing opioid addiction. Researchers followed 240 participants for a year, tracking how often they used opioids. The goal was to see if stab…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated May 26, 2026 02:57 UTC
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New program aims to prevent nurse suicide by building mental strength
Symptom relief CompletedThis study tested whether an online screening tool plus a resiliency program called MINDBODYSTRONG could reduce suicide risk and depression in nurses. Nearly 850 nurses who were at moderate to high risk for suicide took part. The program taught cognitive-behavioral skills through…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 26, 2026 03:01 UTC
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One-Hour talk could save teens from suicide: new study
Symptom relief CompletedThis study tested whether a single one-hour crisis planning session can help teens who are thinking about suicide. Fifty-seven teens aged 14-18 were randomly assigned to receive the plan in person, by video call, or standard care. Researchers checked if teens used the plan and tr…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 26, 2026 02:55 UTC
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Pocket-Warmed epidurals: faster labor pain relief?
Symptom relief CompletedThis study tested if warming epidural medication in a pocket before giving it can speed up pain relief during labor. 139 women with a single baby at full term took part. Researchers measured how quickly pain dropped to a low level and checked satisfaction and side effects.
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 26, 2026 02:54 UTC
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New resilience training aims to curb binge drinking on campus
Symptom relief CompletedThis study tested a program called IMPROVE that teaches college students how to manage stress and uncertainty, with the goal of reducing heavy drinking. 40 students who drank heavily and felt anxious took part. The program was delivered via mobile phone surveys and lab tests to s…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 26, 2026 02:51 UTC
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Smart sensors could ease nurse workload in intensive care
Symptom relief CompletedThis study looked at whether using continuous glucose monitors (CGM) alongside standard finger-stick tests is practical for ICU patients with high blood sugar or on IV insulin. Researchers tracked how often blood sugar stayed in a healthy range and how often it dropped too low. T…
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 26, 2026 02:47 UTC
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Can a common drug clear long COVID brain fog?
Symptom relief CompletedThis study tested whether amantadine, a drug used for other conditions, can help with memory and thinking problems (brain fog) in people with Long COVID. 64 adults with Long COVID and cognitive issues took part. Researchers also looked at mood changes and side effects, and collec…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 22, 2026 14:02 UTC
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New contact lens comfort showdown: PRECISION7 takes on acuvue oasys
Symptom relief CompletedThis study tested how comfortable and clear PRECISION7 contact lenses feel compared to Acuvue Oasys lenses. 71 nearsighted adults who already wore Acuvue Oasys switched to PRECISION7 for two weeks. They filled out surveys about dryness and comfort to see if the new lenses felt be…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 22, 2026 13:55 UTC
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Can parents boost autism therapy at home? new study explores.
Symptom relief CompletedThis study looked at whether teaching parents to use imitation training at home helps young children with autism more than therapist-only sessions. 18 children aged 2-5 took part. The goal was to improve imitation, social communication, and reduce parent stress.
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Higher dose of painkiller may cut morphine use after C-Section
Symptom relief CompletedThis study tested whether a higher dose of ketorolac (60 mg vs. 30 mg) given right after a C-section reduces the need for morphine in the first 24 hours. 92 women who had a C-section under regional anesthesia took part. The goal was to find a better way to manage pain and limit o…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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New study seeks best way to numb skin before epidural in labor
Symptom relief CompletedThis study looked at 51 women in labor who wanted an epidural for pain relief. Researchers compared two standard methods of numbing the skin with lidocaine before inserting the epidural needle: one injection just under the skin (intradermal) and one deeper into the fat layer (sub…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 18, 2026 12:08 UTC
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Fasting for clearer skin? study tests Time-Restricted eating for psoriasis
Symptom relief CompletedThis study looked at whether intermittent fasting (eating only during certain hours) can reduce disease severity and improve quality of life for people with psoriasis and psoriatic arthritis. Sixty overweight adults were randomly assigned to either follow an intermittent fasting …
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Can bifocal contacts tame nearsightedness? new study digs deep
Knowledge-focused CompletedThis study looked at how nearsightedness (myopia) gets worse over time and how soft bifocal contact lenses might help slow it. Researchers measured eye growth, light exposure, and pupil responses in 248 people who were already part of a larger lens study. The goal was to find out…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 03:01 UTC
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Sleep drug shows promise in rewiring stress response in alcohol disorder
Knowledge-focused CompletedThis early-stage study tested whether suvorexant, a sleep aid, could change how the brain and body react to stress in people with moderate to severe alcohol use disorder. 81 adults took either the drug or a placebo nightly for 4 weeks, while researchers measured their startle res…
Phase: EARLY_PHASE1 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:59 UTC
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Can we predict glaucoma drug success? new study investigates
Knowledge-focused CompletedThis study involved 59 adults with glaucoma or high eye pressure to understand why some people respond better to eye pressure-lowering drugs. Researchers measured eye fluid production, drainage, and vein pressure before and after treatment. The goal is to find biomarkers that hel…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:57 UTC
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New study aims to bridge child welfare and addiction services for struggling families
Knowledge-focused CompletedThis study looked at how to help child welfare agencies and substance use programs work together better to support families affected by the opioid crisis. Researchers worked with 9 professionals who provide training and support to these agencies. They created a guide to help lead…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:57 UTC
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Dermatologist on call: could teledermatology save patients from unnecessary hospital stays?
Knowledge-focused CompletedThis study looked at whether having a dermatologist review patients remotely (teledermatology) could help emergency room doctors better distinguish cellulitis (a real skin infection) from pseudocellulitis (a condition that looks like cellulitis but isn't). The goal was to see if …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:55 UTC
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Tiny study peers into brains of kids with autism during therapy
Knowledge-focused CompletedThis small pilot study looked at how routine occupational therapy changes brain activity and behavior in children with autism. Researchers used brain wave recordings (EEG) and parent questionnaires to measure sensory processing and attention. Only 2 children participated, so the …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Bring a buddy to boost bariatric results?
Knowledge-focused CompletedThis study looked at whether having a partner or support person attend bariatric surgery clinic visits helps patients lose more weight and stick to healthy habits. 63 adults preparing for or recovering from bariatric surgery were split into groups that either brought a support pe…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:54 UTC
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Can online training help parents of preemie toddlers? study says maybe.
Knowledge-focused CompletedThis study looked at whether a web-based program called ezParent, with or without extra phone coaching, helps parents of toddlers born very preterm (before 32 weeks). About 452 parents took part, and researchers checked parenting skills, stress, and child behavior over 12 months.…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:53 UTC
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Brain scans reveal how mindfulness rewires PTSD Patients' minds
Knowledge-focused CompletedThis study looked at how a type of talk therapy called mindfulness-based cognitive therapy (MBCT) changes brain activity in people with posttraumatic stress disorder (PTSD). 61 adults with PTSD received either MBCT or a comparison mind-body therapy. Researchers used brain scans t…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:51 UTC
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Can a shared reading program boost literacy in kids with hearing loss?
Knowledge-focused CompletedThis study tested a reading program called Sit Together and Read (STAR) for 15 children aged 4-5 with hearing loss. Caregivers read with their child for 15 weeks using the program. The goal was to see if it helps children learn about letters and words, and to find out what challe…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Can mindfulness training boost first responders' mental toughness?
Knowledge-focused CompletedThis study tested an 8-week mindfulness program for first responders (like police and firefighters) to see if it could lower stress, build resilience, and reduce body pain. 29 active first responders took part in virtual sessions and used a smartphone app. The goal was to learn w…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Wearing activity monitors reveals hidden links to Well-Being in severe obesity
Knowledge-focused CompletedThis study looked at how physical activity relates to quality of life and mental health in 38 adults with severe obesity (BMI over 40). Participants wore activity monitors for 6 weeks to track sitting, standing, and movement. The goal was to understand these connections, not to t…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:47 UTC
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Researchers ask: what do adults with memory worries want from online wellness programs?
Knowledge-focused CompletedThis study aimed to create online mindfulness and lifestyle education programs for adults aged 50+ who have memory concerns but normal thinking skills. Participants joined focus groups to share their views on healthy living and web-based programs. Their feedback helped refine the…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:46 UTC
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Massive ER study aims to stop missed dizziness diagnoses
Knowledge-focused CompletedThis study tested a new way to help emergency room doctors better diagnose and treat dizziness. Over 90,000 adults took part. The goal was to see if training and tools could improve care for common causes like BPPV, inner ear problems, and stroke.
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:46 UTC
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Dental implant study seeks best way to strengthen jawbone
Knowledge-focused CompletedThis study looked at two common methods dentists use to increase bone in the jaw before placing a dental implant. Researchers compared healing, bone density, and patient comfort between the two techniques. The study involved 28 healthy adults who were already scheduled for a dent…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:45 UTC
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Dilated or not? new study seeks best eyeglass prescription method for down syndrome
Knowledge-focused CompletedThis study looked at whether using eye drops to widen the pupils (dilation) helps get a more accurate glasses prescription for people with Down syndrome. Many people with Down syndrome have unique eye shapes that standard eye exams may miss. The researchers compared glasses made …
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 26, 2026 02:45 UTC
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ER overhaul for seniors: quick checks may boost quality of life
Knowledge-focused CompletedThis study tested a new way to help older adults (65+) in the emergency room. First, doctors quickly checked for fall risk, confusion, and frailty. Patients who needed more help then got a full team assessment from specialists. The goal was to see if this approach could improve p…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 14:05 UTC
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Brain games before surgery may predict delirium risk in seniors
Knowledge-focused CompletedThis study looked at whether older adults (60+) can play a short set of brain-training games on a tablet before major surgery. The goal was to see if their first-time performance could help predict who might experience confusion (delirium) after the operation. Researchers tested …
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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Fatty foods before surgery may cloud older brains, study suggests
Knowledge-focused CompletedThis study looked at whether eating high-fat foods before major surgery is linked to inflammation and memory or thinking problems afterward. Researchers tracked 62 older adults (age 60+) having abdominal, pelvic, or joint surgery. They measured diet, inflammation markers, and cog…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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One-Hour talk could change suicide risk, brain study shows
Knowledge-focused CompletedThis study tested whether a one-hour crisis response planning session can reduce suicide risk better than standard care. 191 adults with current suicidal thoughts were randomly assigned to one of the two approaches. Researchers used brain scans and surveys to track changes in emo…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Long COVID brain fog study reveals Real-World treatment outcomes
Knowledge-focused CompletedThis study followed 171 people with Long COVID who had memory or thinking problems. Researchers looked at what treatments they received and how their quality of life changed over 6 months. The goal was to learn which approaches might help, not to test a new drug or cure.
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Contact lens study sees how eyes focus up close
Knowledge-focused CompletedThis study looked at how different types of multifocal contact lenses change the way young adults focus their eyes up close. Twenty people aged 18 to 30 with healthy eyes took part. Researchers compared lenses with the reading power in the center versus the edge to see which help…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 22, 2026 13:50 UTC
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Eggs and spinach: a power pairing for vitamin e?
Knowledge-focused CompletedThis study looked at whether eating eggs with spinach helps the body absorb more vitamin E. Eight healthy adults ate specially labeled spinach, sometimes with eggs. Researchers measured vitamin E levels in their blood to see if the eggs made a difference. The goal was to find a s…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC
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New daily contact lens puts comfort to the test
Knowledge-focused CompletedThis study looked at how comfortable a new daily disposable contact lens feels for people who normally wear monthly lenses. 34 current contact lens wearers tried the new lens and rated their comfort on a scale. The goal was to see if the switch to a daily lens with a special wate…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC
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Taxing marijuana: study reveals how prices change buying habits
Knowledge-focused CompletedThis study looked at how different tax rates and types affect how much marijuana people say they would buy. About 4,700 adults and teens answered survey questions about their purchase choices under various tax scenarios. The goal was to understand how taxes might influence buying…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC
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Can a smartphone app teach teens to manage diabetes?
Knowledge-focused CompletedThis study tested a mobile app that teaches teens with type 1 diabetes how to manage their condition. Twenty young people used the app at home for 12 weeks. Researchers measured how often they used the app and checked their blood sugar control. The goal was to see if the app help…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New study measures nerve loss in SMA adults without offering treatment
Knowledge-focused CompletedThis study looked at 67 adults with spinal muscular atrophy (SMA) types 2 and 3 to see how well special electrical tests (MUNE and CMAP) can measure nerve damage over time. Participants did not receive any treatment; the goal was simply to learn if these tests are good at trackin…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Papaya vs. carrot: which fruit packs a better nutrient punch?
Knowledge-focused CompletedThis study looked at how well the body absorbs carotenoids (natural pigments that can become vitamin A) from papaya, tomato, and carrot. Sixteen healthy adults ate a meal containing one of these foods, and researchers measured carotenoid levels in their blood afterward. The goal …
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC