Ohio State University
Clinical trials sponsored by Ohio State University, explained in plain language.
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Grocery delivery & counseling tested to fight chronic disease in Low-Income patients
Disease control CompletedThis study tested a 24-week support program for Medicaid patients with conditions like high blood pressure, diabetes, and kidney disease. The program provided healthy food deliveries, nutrition counseling, and help with other social needs. Researchers wanted to see if this approa…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Apr 02, 2026 14:58 UTC
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Sleep pill studied to calm stress and curb drinking
Disease control CompletedThis study tested if suvorexant, a medication used for insomnia, could help people with moderate to severe alcohol use disorder. Researchers wanted to see if the drug could reduce the brain's overreaction to stress and lower heavy drinking days. 81 participants took either the dr…
Phase: EARLY_PHASE1 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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ERs test special team approach to stop older patients from declining after visits
Disease control CompletedThis study tested a two-step program in an emergency department to better care for patients aged 65 and older. First, nurses quickly screened patients for risks like falls, confusion, and frailty. Those with concerning results received a more thorough assessment from a specialize…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New monitor could free up ICU nurses from constant finger pricks
Disease control CompletedThis study tested whether using a continuous glucose monitor (CGM) in the intensive care unit (ICU) is practical and helpful. It compared 100 ICU patients using the CGM to 100 past patients who used traditional fingerstick checks. The goal was to see if the CGM improved blood sug…
Phase: PHASE1, PHASE2 • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Mindfulness & diet program aims to ease double burden for black caregivers
Disease control CompletedThis small, completed pilot study tested a telehealth program designed to help Black women who are caregivers for family members with dementia. The program combined mindfulness exercises and a heart-healthy diet plan (DASH) to see if it could help them manage their chronic stress…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Can a cup of green tea fix your gut and fight inflammation?
Disease control CompletedThis study tested whether taking a green tea extract supplement for one month could improve gut health and reduce harmful inflammation in people with metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. Forty-six participants, including some …
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Could a milk ingredient fix your gut and lower blood sugar?
Disease control CompletedThis study tested whether adding a natural component from milk fat (MFGM) to the diet could help adults with metabolic syndrome. Participants drank either the special milk or a regular milk for two weeks while eating a controlled diet. Researchers measured blood sugar, gut health…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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Can a phone app curb campus binge drinking?
Disease control CompletedThis study tested a new program called IMPROVE, designed to help college students who drink heavily and feel stressed. The program teaches skills to better handle anxiety and uncertainty, aiming to reduce the urge to use alcohol as a coping method. Researchers compared the progra…
Phase: NA • Sponsor: Ohio State University • Aim: Disease control
Last updated Feb 20, 2026 14:44 UTC
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Eye dilation study aims for clearer vision for down syndrome community
Diagnosis CompletedThis study tested whether dilating the eyes (using drops to widen the pupil) gives a better measurement for glasses prescriptions in people with Down syndrome. People with Down syndrome often have unique eye shapes that make standard vision tests less accurate. Researchers compar…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Diagnosis
Last updated Mar 27, 2026 12:40 UTC
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Can a home stop addiction before it starts? landmark trial tests housing as prevention for homeless youth
Prevention CompletedThis study tested whether providing stable housing along with counseling and support services could prevent opioid addiction in homeless young adults. Researchers worked with 240 homeless youth aged 18-24 who were not yet addicted to opioids. They compared two groups: one receive…
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 30, 2026 14:35 UTC
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Virtual lifeline for teens in crisis: can a One-Hour plan save lives?
Prevention CompletedThis study tested whether a one-hour virtual crisis planning session could help prevent suicide in teens. It involved 57 adolescents who were actively thinking about suicide. Researchers compared the virtual session to an in-person version and standard care to see which was more …
Phase: NA • Sponsor: Ohio State University • Aim: Prevention
Last updated Mar 24, 2026 12:02 UTC
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Could a buddy system boost bariatric surgery success?
Symptom relief CompletedThis study tested whether having a partner or support person attend medical appointments with patients preparing for weight loss surgery was helpful. Researchers wanted to see if this extra support led to better weight loss, healthier habits, and improved relationships after surg…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Can mindfulness be a lifeline for stressed first responders?
Symptom relief CompletedThis study tested whether a special mindfulness program could help first responders manage job stress and physical discomfort. Twenty-nine active first responders took part in an 8-week online mindfulness course and used a companion app for six months. Researchers measured change…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 02, 2026 14:58 UTC
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Which contact lens feels better? study tests two brands
Symptom relief CompletedThis study compared how comfortable two different brands of reusable contact lenses feel for people with nearsightedness. 71 participants who normally wore Acuvue Oasys lenses tried Precision7 lenses for two weeks. Researchers measured comfort levels through vision tests and surv…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Pocket-Warmed pain relief: a faster start for laboring moms?
Symptom relief CompletedThis study tested a simple idea: does warming epidural pain medication in a doctor's pocket before giving it help the medicine work faster for women in labor? Researchers enrolled 139 women to compare the speed of pain relief between warmed and room-temperature medication. The go…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Finding the right dose: study tests pain relief options for new moms after C-Section
Symptom relief CompletedThis study aimed to find the best dose of the pain medication ketorolac for women recovering from cesarean delivery. Researchers compared whether a 30mg or 60mg dose given right after surgery better reduced the need for opioid painkillers in the first 24 hours. The trial involved…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:32 UTC
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Which numbing shot hurts less before your epidural?
Symptom relief CompletedThis study aimed to find out which method of giving a numbing shot causes less pain right before placing the epidural needle during labor. Researchers compared injecting lidocaine just under the skin versus into a deeper skin layer in 51 women in labor. They measured pain using p…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:31 UTC
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Could a new daily lens feel better than your monthly ones?
Symptom relief CompletedThis study tested how comfortable a new type of daily disposable contact lens felt for people who usually wear monthly lenses. Thirty-four participants tried the new lenses, which have a special water surface treatment. Researchers asked them to rate their comfort to see if the d…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC
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Could a common drug clear long COVID brain fog?
Symptom relief CompletedThis study tested whether amantadine, an existing medication, could help improve thinking problems like memory loss and poor concentration (often called 'brain fog') in people with Long COVID. For four months, 64 participants were randomly assigned to receive either amantadine or…
Phase: PHASE2 • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Mar 27, 2026 12:40 UTC
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Scientists search for clues to predict glaucoma drug success
Knowledge-focused CompletedThis study aimed to understand why eye pressure responds differently to standard glaucoma medications in different patients. Researchers measured how eye fluid is produced and drains in 59 people with ocular hypertension or early glaucoma. The goal was to find measurements that c…
Phase: PHASE4 • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 03, 2026 19:55 UTC
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Doctors track what actually helps long COVID 'Brain Fog'
Knowledge-focused CompletedThis study looked back at medical records and followed patients to see which treatments helped people with Long COVID who have thinking problems like brain fog or memory loss. Researchers at Ohio State University tracked 171 patients to see if treatments like therapy, medication,…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC
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Can a quick brain game predict Post-Surgery confusion?
Knowledge-focused CompletedThis study tested whether a short, 6-game brain exercise on a laptop is a practical way to measure older patients' mental sharpness before major surgery. Researchers wanted to see if the game scores could help predict who might experience sudden confusion (delirium) after their o…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Researchers craft online brain health programs based on user feedback
Knowledge-focused CompletedThis study aimed to create and refine two online, self-paced programs: one focused on mindfulness meditation and another on general lifestyle education. Researchers worked with 23 adults aged 50+ who reported early memory concerns but had normal test scores. Participants joined f…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:58 UTC
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Researchers test phone app to coach teens on diabetes care
Knowledge-focused CompletedThis study tested whether a new mobile app could help young people with type 1 diabetes learn better self-management skills. Twenty youth aged 10-18 used the educational app at home for 12 weeks, completing weekly scenarios. Researchers tracked how often participants used the app…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Papaya put to the test: is it a superfood for nutrient absorption?
Knowledge-focused CompletedThis study aimed to find out if papaya is a better source of carotenoids (healthy plant nutrients) than more common foods like carrots and tomatoes. Researchers measured nutrient levels in the blood of 16 healthy volunteers after they ate meals containing these foods. The goal wa…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Apr 02, 2026 14:57 UTC
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Scientists scan brains to unlock how mindfulness helps trauma
Knowledge-focused CompletedThis study aimed to understand how mindfulness-based therapy affects brain activity in people with post-traumatic stress disorder (PTSD). Researchers compared two types of group therapy delivered over 8 weeks via video calls. They used brain scans and surveys to measure changes b…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Dental study pits two Bone-Building methods Head-to-Head
Knowledge-focused CompletedThis study compared two established surgical techniques used to build up jawbone before placing a dental implant. Researchers observed 28 healthy adults to see if one method led to better healing, higher bone density, or a more comfortable patient experience. The study did not ch…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Could your Pre-Surgery diet affect your brain afterward?
Knowledge-focused CompletedThis study looked at whether eating a high-fat diet before major surgery is linked to higher body inflammation and an increased risk of thinking problems or confusion after the operation. Researchers enrolled 62 older adults having surgeries like joint replacements or abdominal p…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Eggs unlock the power of spinach: study finds key to boosting vitamin e
Knowledge-focused CompletedThis study aimed to see if eating eggs with spinach helps your body absorb more Vitamin E, a nutrient many people don't get enough of. Researchers gave healthy volunteers spinach with different amounts of eggs or other fats and then measured Vitamin E levels in their blood over s…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Can a special reading plan unlock literacy for deaf kids?
Knowledge-focused CompletedThis study tested whether a home-based reading program could help young children with hearing loss learn early reading skills. Fifteen families participated, with caregivers trained to read to their child four times a week using specific techniques. The goal was to see if this ap…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists scan brains to see how autism therapy works
Knowledge-focused CompletedThis small pilot study aimed to understand what happens in the brain during occupational therapy for children with autism. Researchers measured brain activity and behavior in children before and after 6-8 weeks of standard therapy. The goal was to see if a child's level of engage…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Scientists map nerve damage in muscle disease to find better treatments
Knowledge-focused CompletedThis study aimed to understand how spinal muscular atrophy (SMA) progresses in adults by measuring electrical signals from their nerves and muscles. Researchers followed 67 adults with SMA, some receiving a new drug and some not, to see how these measurements changed over time. T…
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 20, 2026 14:48 UTC
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Researchers test if special contact lenses can help young adults focus their eyes
Knowledge-focused CompletedThis study aimed to understand how different designs of multifocal contact lenses affect the eye's ability to focus, particularly for people with focusing problems. Researchers compared two lens types—one designed for near vision in the center and another for distance vision in t…
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 05, 2026 13:59 UTC