Ohio State University

This study aims to understand how Ohio's START program helps rural families where a parent struggles with substance use. Researchers will follow 400 families for a year to see if connecting parents to nearby treatment services and providing peer mentors leads to reduced substance…

This study is testing a new support program called TBI-RECOVER for people with both a brain injury and a substance use disorder. It will train therapists to screen for brain injuries and adjust their therapy methods to help patients stay in treatment longer. The goal is to see if…

This study aims to find out if a shorter, 3-day course of antibiotics is just as effective as the standard 7-day course at preventing infections in men who need prostate surgery. It will involve 250 men who already have a urinary catheter and are scheduled for a specific laser pr…

This study is testing if a one-time booster dose of the Gardasil-9 vaccine can help adults with recurrent respiratory papillomatosis (RRP) go longer between needed surgeries. RRP causes non-cancerous growths in the throat and airways, often requiring repeated procedures. The rese…

This study aims to find out if a new nutrition supplement formula works better than a standard one for adults with cystic fibrosis. Researchers will compare how well the body absorbs and uses special versions of key nutrients like vitamins D and E, copper, and choline. About 60 p…

This study is testing whether a high-tech computer analysis of a child's eye can create a better glasses prescription than a standard eye exam. It will involve 24 children with Down syndrome, aged 5 to 12. Each child will try two different pairs of glasses for two months each to …

This study will test whether adding 12 virtual health coaching sessions over 16 weeks helps people recovering from heart attacks or heart failure. Researchers want to see if coaching improves weight management, reduces stress, increases medication adherence, and lowers hospital r…

This early-stage study is testing whether a combination of two existing drugs, dasatinib and quercetin, is safe and might help improve physical movement and thinking skills in older adults with progressive multiple sclerosis. The drugs aim to clear out old, damaged 'senescent' ce…

This study is testing if a single oral dose of a drug related to psilocybin (the psychedelic compound in 'magic mushrooms') can help reduce symptoms of depression and anxiety. It will involve 40 adults with major depressive disorder who haven't gotten enough relief from their cur…

This study is testing whether eating one special cookie per day for eight weeks can improve sleep quality in overweight adults who have trouble sleeping. The cookies are made with an oil high in linoleic acid, a type of fat that may have health benefits. Researchers will measure …

This study is testing a home-based program to see if it can improve physical activity, sleep, and endurance in young children (ages 1-6) with severe motor delays, like cerebral palsy. Children will use a special supportive stander three times a week for eight weeks, with one week…

This study examines existing dental records to understand how dental implants are positioned compared to natural teeth. Researchers will analyze X-rays and scans from 400 patients who received molar implants, comparing implant angles to both the original tooth and the matching to…

This study aims to better understand how gums heal after a common surgery for gum recession. Researchers will observe 15 patients who are already scheduled for the procedure, taking non-invasive scans and saliva samples to track swelling, blood flow, and healing markers. The goal…

This study aims to understand how gum surgery affects inflammation levels in the bloodstream. Researchers will compare blood samples from 30 patients undergoing either surgical gum treatment or a standard non-surgical cleaning. By measuring specific inflammation markers at differ…

This study aims to better understand how early memory concerns progress over time in older adults from underserved communities. Researchers will follow 1,000 adults aged 50+ who have been diagnosed with early memory changes but not dementia. Participants will complete annual chec…