Ohio State University

This study looks at two different bone graft mixtures used during sinus lifting surgery to prepare the upper jaw for dental implants. Ten healthy, non-smoking adults will receive both mixtures—one on each side of their jaw—so healing can be compared directly. Researchers will che…

This study looks at whether a special nutrition supplement can improve nutrient levels in adults with cystic fibrosis. Researchers will compare two different formulas to see which one works better. Participants will take the supplement for 6 weeks and have blood tests before and …

This study compares two new suction-equipped tools (FANS and CVAC) for removing medium-to-large kidney stones. About 159 adults with stones 8-20 mm will be randomly assigned to one device. The main goal is to see which tool leaves the kidney more stone-free, as confirmed by CT sc…

This study looks at whether taking antibiotics for 3 days before prostate surgery works as well as the usual 7 days to prevent infections. Men who have a urinary catheter and are scheduled for a specific type of prostate surgery (HoLEP) will be randomly assigned to one of two gro…

This study tests a natural material made from your own blood, called Platelet-Rich Fibrin (PRF), to improve healing after tooth removal. Fourteen adults needing two teeth extracted will receive a bone graft with PRF in one socket and a standard graft in the other. Researchers wil…

This study tests a program that delivers fresh produce to the homes of pregnant women with type 1 or 2 diabetes who also struggle to get enough healthy food. Participants will also receive group education on diabetes, nutrition, and cooking, plus ongoing support for other needs. …

This study looks at 500 adults in the emergency room with dangerously low oxygen levels. It compares two non-invasive breathing supports: a pressurized face mask and high-flow nasal oxygen. The goal is to see which method improves survival, reduces time on a breathing machine, an…

This study tests whether a single booster dose of the Gardasil-9 vaccine can lengthen the time between surgeries for adults with recurrent respiratory papillomatosis (RRP), a condition where non-cancerous growths recur in the airway. Researchers will enroll 50 adults who have alr…

This study looks at two common ways dentists uncover dental implants during a small gum surgery. Sixteen adults with two ready-to-uncover implants will get one method on each implant so doctors can compare healing, gum thickness, and appearance over one year. The goal is to find …

This study tests whether a single oral dose of CYB003, a drug similar to psilocybin (found in magic mushrooms), can help relieve symptoms of depression and anxiety. Forty adults with major depressive disorder and moderate-to-severe anxiety will receive either CYB003 or a placebo.…

This study compares two ways to prescribe glasses for children with Down syndrome, ages 5 to 12. One method uses computer analysis of eye images, the other uses standard clinical exams. The goal is to see which approach gives better vision. The study involves 24 children and is n…

This study tests whether eating special healthy cookies high in linoleic acid for 8 weeks can improve sleep quality in overweight adults with insomnia. Sixteen participants will eat cookies daily and have their sleep, blood fats, and activity levels measured. The goal is to see i…

This early-stage study tests whether a combination of two drugs (dasatinib and quercetin) is safe and can help improve physical and thinking abilities in older adults with secondary progressive multiple sclerosis (MS). The drugs work by removing aged, damaged cells that may fuel …

This study looks at whether 12 virtual health coaching sessions over 16 weeks can improve the health and well-being of people with heart disease, such as heart failure or a recent heart attack. Researchers will compare those who get coaching plus standard care to those who only g…

This study will follow 1,000 older adults (age 50+) from under-resourced communities who have early memory concerns. Researchers will collect health data, brain scans, and samples over time to learn how memory problems progress. The goal is to better understand dementia risk in g…

This study will measure inflammatory molecules in the blood of 30 adults before, during, and after gum surgery or a non-surgical gum treatment. The goal is to understand how the body responds to the stress of dental procedures. Participants will give blood samples at several time…

This study looks at a program called TBI-RECOVER that screens people in substance use treatment for brain injuries and provides special support. Researchers want to see if this helps patients stay in treatment longer and feel better. About 900 patients and their providers will ta…

This pilot study tests whether a specially designed family therapy program is practical and helpful for women with opioid use disorder who are also involved in the justice system and sex trade. About 120 women and a family member will be randomly assigned to either the family the…

This study looks at dental records to see how the angle of a single molar implant compares to the original tooth or the same tooth on the other side. No new participants are enrolled; researchers will review existing images from about 400 patients. The goal is to understand typic…