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Magic Mushroom-Like drug could ease depression and anxiety in one dose

NCT ID NCT06820723

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tests whether a single oral dose of CYB003, a drug similar to psilocybin (found in magic mushrooms), can help relieve symptoms of depression and anxiety. Forty adults with major depressive disorder and moderate-to-severe anxiety will receive either CYB003 or a placebo. Researchers will use brain scans (fMRI, EEG) and questionnaires to measure changes in brain activity and mood.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ohio State University Department of Psychiatry

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.