Medical College Of Wisconsin

This study tested a combination of three existing drugs (rucaparib, bevacizumab, and atezolizumab) for women with recurrent or progressive endometrial cancer that had stopped responding to prior treatment. The goal was to see if using these drugs together could shrink tumors and …

This study tested an experimental cell therapy for adults with multiple myeloma whose cancer did not respond well enough to a prior stem cell transplant and standard maintenance therapy. Doctors collected and reprogrammed the patients' own immune cells (CAR T-cells) to target the…

This study tested a shorter, more intense schedule of radiation therapy given before surgery for soft tissue sarcomas in the arms, legs, or chest wall. The goal was to see if this approach could control the cancer as well as standard, longer radiation while being more convenient …

This study tested a support program designed to help low-income African Americans manage diabetic kidney disease. The program provided education, lifestyle coaching, and a 'navigator' to help participants access basic needs like food and stable housing. Researchers wanted to see …

This study tested whether group sessions for friends who all have HIV could help them stay in medical care and take their medication consistently. Researchers in Russia worked with 341 people living with HIV, organizing them into friend networks. They compared group support sessi…

This early-stage study tested whether a traditional Chinese herbal formula called Anti-tumor B could slow the growth of oral cancer cells. Thirty adults with oral cancer scheduled for surgery took the herbal pills for 7 to 28 days before their operation. Researchers compared tumo…

This study tested whether a daily probiotic supplement could improve blood vessel function and reduce markers of inflammation in people with coronary artery disease or type 2 diabetes. Researchers enrolled 215 participants to see if changing gut bacteria could help control heart …

This study tested whether tildrakizumab, a drug approved for psoriasis, could prevent graft-versus-host disease (GVHD) in patients receiving stem cell transplants for blood cancers. The trial involved 51 adults who received the drug alongside their transplant to see if it could r…

This study aimed to find out if a much shorter course of radiation therapy could be safely given after surgery for head and neck cancer. It tested reducing treatment from the standard six weeks down to just one week for 18 patients. The main goal was to check if the shorter treat…

This small pilot study tested a new order of treatment for patients with 1 to 4 brain tumors that have spread from other cancers. Instead of the usual surgery followed by radiation, researchers gave a precise, high-dose radiation treatment first, then performed surgery within 10 …

This study tested a new, potentially safer drug combination to prepare patients for a half-matched bone marrow transplant. It involved 43 adults with blood cancers like multiple myeloma who could not tolerate standard high-dose treatments. The goal was to see if this gentler prep…

This study tested a new type of swab to see if it works well for collecting cells for anal cancer screening. Researchers compared inserting the swab 3 cm versus 5 cm deep to see which depth collects better cell samples and is more comfortable for users. The goal is to find a reli…

This study tested whether freezing nerves during robotic lung surgery helps reduce pain afterward. Researchers compared the new freezing technique to standard pain care in 33 patients. The goal was to see if it lowered pain scores and reduced the need for opioid painkillers durin…

This small pilot study tested whether a combination of gentle, non-invasive brain stimulation and computer-based memory training was a practical approach for people with mild cognitive impairment (MCI). Eight participants aged 50-90 with early memory loss completed the study. The…

This study tested whether adding mild electrical brain stimulation to standard speech therapy helps people with long-term speech problems after a stroke. Twenty-five adults with chronic aphasia received either real or sham stimulation during therapy sessions while their brains we…

This study tested whether a small, non-invasive stimulator placed on the outer ear could reduce nausea in teenagers with functional gastrointestinal disorders. 109 teens participated, with half receiving an active device and half receiving a fake one for comparison over four week…

This study tested whether adding a second type of nerve block to a standard pain control method improves recovery after heart surgery. Researchers compared pain levels, opioid medication use, and breathing function in 62 patients who received either one or two types of nerve bloc…

This small pilot study tested whether a non-invasive device that stimulates nerves in the ear could help people with cyclic vomiting syndrome (CVS). CVS causes severe, recurring episodes of nausea, vomiting, and pain. Researchers compared the effects of the real stimulator to a f…

This study observed women who developed severe heart failure (cardiogenic shock) around the time of childbirth. Researchers compared the recovery of women who received a temporary heart pump device (Impella) to those who received standard medical care. The goal was to understand …

This study aimed to understand if non-calorie artificial sweeteners, commonly used by people with type 1 diabetes, are linked to body composition and blood sugar control. Researchers measured body fat, muscle, and blood markers in 21 youth with type 1 diabetes and asked detailed …

This study tested whether a new artificial intelligence (AI) tool could help train new doctors in performing ultrasound-guided nerve blocks, a common anesthesia technique. Twenty anesthesia residents with no prior experience used the AI device during their training. Researchers w…

This study tested whether sending an animated video by text message helps parents prepare for difficult conversations with doctors when their pregnancy involves a fetal anomaly. Researchers compared 48 parents who received the video to those who got standard webpage links, measur…

This study tested if giving surgeons real-time feedback about the inner ear's response to sound during cochlear implant surgery leads to better outcomes. It involved 88 people getting a cochlear implant, who were randomly assigned to have the feedback system on or off during thei…