CAR T-Cell therapy shows promise for Hard-to-Treat multiple myeloma
NCT ID NCT05032820
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 26 times
Summary
This study tested a new treatment called anti-BCMA CAR T-cells (bb2121) in 40 adults with multiple myeloma who had a poor response after a stem cell transplant and maintenance therapy. The goal was to see if this one-time cell therapy could help achieve a complete remission. While it may improve outcomes, patients may still need ongoing management, so it is not a cure.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College and Medicine
Houston, Texas, 77030, United States
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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City of Hope National Medical Center
Duarte, California, 91010, United States
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Duke University Medical Center
Durham, North Carolina, 27705, United States
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H. Lee Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Loyola University Medical Center
Maywood, Illinois, 60153, United States
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Mount Sinai Medical Center
New York, New York, 10029, United States
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Roswell Park Cancer Center
Buffalo, New York, 14203, United States
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Stanford Hospital and Clinics
Palo Alto, California, 94305, United States
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University of California, San Francisco
San Francisco, California, 94143, United States
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University of Pennsylvania Hospital Center
Philadelphia, Pennsylvania, 19104, United States
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University of Virginia
Charlottesville, Virginia, 22908, United States
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University of Wisconsin Hospitals and Clinics
Madison, Wisconsin, 53792, United States
Conditions
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