Medical College Of Wisconsin

This study tested the drug pacritinib in 6 men whose prostate cancer had returned after surgery or radiation, shown by rising PSA levels. The goal was to see if the drug could delay further PSA increases. The trial was terminated early, so results are limited.

This early-phase study tested a personalized cell therapy (CAR-T) that targets two proteins, CD19 and CD20, on leukemia cells. It involved 5 patients with B-cell acute lymphoblastic leukemia that had returned or not responded to standard treatments. The main goal was to check saf…

This early-phase study tested a drug called CPI-613 combined with chemotherapy and radiation for people with pancreatic cancer that cannot be removed by surgery. The goal was to find the safest dose and see if the combination helps control the tumor. Only 8 people took part befor…

This study tested a chemotherapy combination containing cladribine for people whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had returned or not responded to prior treatment. The goal was to see if the treatment could wipe out signs of the disease …

This study tested a small device that sends mild electrical pulses to nerves in the ear to help people with cyclic vomiting syndrome (CVS) during an episode. The goal was to reduce severe belly pain, nausea, and vomiting, and to lower the need for opioid painkillers. Only 4 peopl…

This study tested a small, non-invasive device placed on the ear to treat paroxysmal sympathetic hyperactivity (PSH) in children aged 2–17 with severe brain injury. PSH causes sudden episodes of racing heart, high blood pressure, sweating, and stiffness. The device aims to calm t…

This study tested a small device that sends mild electrical pulses to the ear to reduce nausea and vomiting caused by chemotherapy in children, teens, and young adults. Researchers measured how severe the nausea was and how many extra medicines were needed. The study was stopped …