Chu De Reims

This study looked at children aged 3 to 15 with overactive bladder caused by nerve issues, often from spinal problems. It compared two different doses of Botox injections into the bladder muscle to see if a lower dose works just as well as a higher dose. The goal was to improve b…

This study looked at whether measuring a substance called amyloid beta 1-40 in spinal fluid can help doctors diagnose Alzheimer's disease more reliably. Current tests sometimes give unclear results. The researchers tested 204 people with memory problems to see if adding this new …

This study looked at 39 ICU patients with low blood volume to see if changes in pulse pressure (a measure from blood pressure readings) could predict whether they would benefit from extra fluids. Doctors used a leg-raising maneuver and echocardiography to check fluid response. Th…

This study looked at 116 people with small-intestine neuroendocrine tumors (carcinoid tumors) to see if a blood test or an overnight urine test works as well as the standard 24-hour urine test for diagnosis. The standard test is accurate but requires collecting all urine for 2-3 …

This study looked at whether a blood test could find genetic changes in people with advanced melanoma. Normally, doctors need to take a piece of the tumor (biopsy) to check for these changes, which can be painful and hard to do. The study tested blood samples from 50 patients to …

This study tested whether a single osteopathic treatment in the emergency room can improve recovery from a mild to moderate ankle sprain. Fifty adults with recent sprains were randomly assigned to either standard medical care or osteopathic manipulation. Researchers measured pain…

This study compared two ways to manage pain after total hip replacement: a newer nerve block called PENG and the standard surgical infiltration. The goal was to see which method reduces the need for strong painkillers like morphine, especially in older patients who are more prone…

This study tested whether wearing a virtual reality headset during an epidural injection for lower back and leg pain could make the procedure less painful and less anxiety-provoking. Researchers compared the experience of 116 patients who received the injection with or without th…

This study looked at 296 cancer patients aged 65 and older to see if a substance in the blood called elastin peptides can help measure frailty. Frailty is hard to judge with current methods, which are often slow and subjective. The goal is to find a more objective way to decide t…

This study explored how deep brain stimulation (DBS) changes the way people with Parkinson's disease explain positive and negative events, known as attributional style. Researchers assessed 32 participants using questionnaires to measure hostility and depression. The goal was to …

This study looked at whether a specific antibody, usually linked to a rare kidney disease, might also show up in people with lupus who have kidney inflammation (lupus nephritis). Researchers tested stored blood samples from 100 people with lupus and healthy donors. The goal was t…

This study looked at whether a specific gene variation (CR1) that affects a blood protein makes people more likely to develop Alzheimer's disease. Researchers compared 200 people—some with Alzheimer's and some without—to see if the gene difference was more common in those with th…

This study looks at pregnancy denial, where a woman is unaware she is pregnant for months or even the whole time. Researchers compared 130 mothers—some who experienced denial and some who did not—to see how it affects the bond between mother and child and the child's early develo…

This study looked at whether a CT scan done 7 days after pancreatic surgery could find complications that doctors might miss. 80 adults who had planned pancreatic surgery were included. The goal was to see if the scan could detect problems like leaks or infections before patients…

This study looked at 125 young adults aged 18-25 to understand what makes someone more likely to binge drink. Researchers used brain scans, genetic tests, and thinking skill assessments to find patterns. The goal is to identify risk factors and improve prevention efforts.

This study looked at how certain natural germ-fighting proteins (antimicrobial peptides) are made in the gums of people with and without chronic gum disease. Researchers collected cheek cell samples from 29 adults aged 35-65 to measure gene activity. The goal was to learn more ab…

This study looked at how thinking skills (like flexibility and self-control) and social understanding (like reading emotions) are linked to alcohol use disorders. Researchers tested 216 people, including those with alcohol problems and healthy volunteers, using tasks and eye-trac…

This study tracked 150 adults who had severe COVID-19 pneumonia to see if they developed long-term lung damage. Researchers used CT scans to check for scarring (interstitial lung disease) in the medium and long term. The goal was to understand how often these complications occur,…

This study looked at how methotrexate, a key rheumatoid arthritis drug, is removed from the body in patients who take it as prescribed. Researchers measured the drug and its main byproduct in urine from 62 patients. The goal was to create a standard reference to help doctors iden…

This study looked at whether the smallest meaningful change in bone density scans is different for people with obesity compared to those without. Researchers measured bone density twice in 120 adults with a BMI over 30. The goal was to improve accuracy when interpreting bone scan…

This study looked at how often bronchiectasis (a lung condition that can cause breathing problems) occurs in people with primary humoral immunodeficiency, a type of immune system disorder. Researchers in France used CT scans and lung function tests on 46 adults to detect bronchie…

This study looked at whether certain genes are linked to a severe form of diabetic eye disease that can cause blindness. Researchers compared 302 adults with type 2 diabetes, some with advanced eye disease and some without. The goal was to find genetic clues that could help predi…

This study looked at tiny cell fragments called microparticles in 24 children with acute lymphoblastic leukemia. The goal was to see if these particles, released when leukemia cells die or blood vessels are damaged, make blood clots more likely during treatment. Researchers measu…

This study looked at skin samples from 20 people with moderate to severe hidradenitis suppurativa (HS) who had surgery. Researchers measured different inflammatory proteins in the lab to better understand what causes the disease and why it comes back. The goal was to gather knowl…

This study looked at 183 cancer patients treated with checkpoint inhibitors to see how often they develop autoantibodies (immune system markers that can attack the body) and related autoimmune diseases. The goal was to better understand and monitor these side effects. No new trea…

This study aimed to better understand hearing loss by measuring electrical signals from the hearing nerve during ear surgery. Researchers studied 19 people with normal hearing or hearing loss who were already undergoing a specific type of brain surgery. They recorded nerve activi…

This study tested whether nurses can safely follow a step-by-step plan using a device that measures carbon dioxide (capnography) to guide when to remove a breathing tube. It included 50 adults in intensive care who needed a ventilator for more than 48 hours. The main goal was to …

This study looked at how well doctors, resident doctors, and nurses check patients' pupils in the intensive care unit. Pupil checks are important for understanding brain health and response to medicines. The researchers compared the healthcare workers' manual checks to a special …

This study looked at whether a type of MRI called diffusion-weighted MRI (DW-MRI) can predict if head and neck cancer will come back after chemoradiotherapy. Researchers scanned 59 patients shortly after treatment and tracked them for up to a year. The goal was to see if early ch…

This study looked at whether a protein called CD160 is found in new blood and lymph vessels that grow in the cornea after a transplant. Researchers examined tissue from 43 patients who had cornea surgery to see if CD160 is linked to graft rejection. The goal was to better underst…

This study looked at whether certain chemicals called organochlorines, which are stored in body fat, are more common in people with pancreatic cancer. Researchers compared 56 patients with and without the disease. The goal was to see if these chemicals might be a risk factor for …

This study looked at 100 adults on hemodialysis (kidney filtering) to understand how certain waste molecules, called AGEs, damage blood vessels and increase heart risk. Researchers measured AGE buildup in blood and skin, checked blood vessel hardening with X-rays, and analyzed ge…

This study looked at how well older adults with early-stage Alzheimer's can drive in real traffic. Researchers compared 60 drivers aged 70+ (half with Alzheimer's, half healthy) to find common mistakes and suggest ways to keep them driving safely. No treatment or cure was tested;…

This study used brain scans (fMRI) to understand why people with bipolar disorder sometimes have disorganized thoughts and speech. Researchers compared 79 participants—some with bipolar disorder and healthy volunteers—while they performed thinking tasks. The goal was to learn mor…

This study looked at whether natural aging of proteins in the walls of blood vessels might play a role in the development of aortic aneurysms (a bulge in the main artery). Researchers collected blood and measured skin autofluorescence in 24 patients undergoing surgery for an abdo…

This study looked at how children born prematurely (before 37 weeks) understand social situations and emotions compared to full-term children. Researchers tested 56 children aged 7-10 on memory, flexibility, and reading others' thoughts. They also measured parents' anxiety and st…

This study tested whether Raman spectroscopy, a non-invasive laser technique, can accurately measure skin fibrosis in people with systemic sclerosis (scleroderma). Twenty-six adults with the disease had their skin scanned with the device. The goal was to see if this method is mor…

This study looked at 254 older adults to see if certain chemical changes in the blood can help identify frailty. Frailty affects many seniors and can lead to dependency, but early detection may help slow decline. Researchers measured specific markers linked to aging to find diffe…

This study checked 150 adults who had adrenal gland lumps found by chance, but no signs of Cushing's disease. Researchers looked for changes in a gene that controls the body's stress hormone receptor. The goal was to find out if these gene changes are more common than previously …