Study links brain function to alcohol addiction risk

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1. AUD patients Inclusion criteria: * Patients between 18 and 60 years old, men or women, following AUD treatment * Having a diagnosis of alcohol use disorder according to DSM-5 criteria * Patients withdrawn of alcohol for at least 15 days * Patients being a native French speaker * Patients enrolled in the national healthcare insurance program * Patients consenting to participate to the study exclusion criteria: * A diagnosis of schizophrenia, of any other chronic psychotic state, or of bipolar disorder according to DSM-5 criteria * The presence of a current depressive episode as defined by DSM-5 criteria * The presence of another substance use disorder during the six months preceding the study, except for tobacco dependence. * The presence of any intellectual disability, of pervasive developmental disorders or learning difficulties (especially of dysphasia and dyspraxia) * The presence of any neurological disorder or any other disorder affecting the central nervous system including Korsakoff syndrome or Wernicke's encephalopathy * Having any uncorrected auditory or visual deficits 2. First-degree relatives of AUD patients Inclusion criteria: * Participants between 18 and 60 years old, men or women * Current and past absence of any alcohol use disorder or any other substance use disorder as defined by DSM-5 diagnostic criteria * Participants having at least one first-degree relative presenting an alcohol use disorder (father or sibling) * Participants being a native French speaker * Participants enrolled in the national healthcare insurance program * Participants consenting to participate to the study exclusion criteria: * The presence of any alcohol use disorder or any other substance use disorder as defined by DSM-5 diagnostic criteria, except for tobacco dependence * A diagnosis of schizophrenia, of any other chronic psychotic state, or of bipolar disorder according to DSM-5 criteria * The presence of a current depressive episode as defined by DSM-5 criteria * The presence of any alcohol use disorder in the participant's biological mother in order to exclude fetal alcohol spectrum disorders due to prenatal alcohol intoxication * The presence of any intellectual disability, of pervasive developmental disorders or learning difficulties (especially of dysphasia and dyspraxia) * The presence of any neurological disorder or any other disorder affecting the central nervous system * Participants having any uncorrected auditory or visual deficits 3. Healthy control participants (the inclusion and non-inclusion criteria of investigation groups 2 and 4 are identical): Inclusion criteria: * Participants between 18 and 60 years old, men or women * Current and past absence of any alcohol use disorder or any other substance use disorder as defined by DSM-5 diagnostic criteria * Participants being a native French speaker * Participants enrolled in the national healthcare insurance program * Participants consenting to participate to the study exclusion criteria: * The presence of any alcohol use disorder or any other substance use disorder as defined by DSM-5 diagnostic criteria, except for tobacco dependence * A diagnosis of schizophrenia, of any other chronic psychotic state, or of bipolar disorder according to DSM-5 criteria * The presence of a current depressive episode as defined by DSM-5 criteria * Having any first-degree relative with alcohol use disorder (parents, siblings, children) according to DSM-5 diagnostic criteria * The presence of any intellectual disability, of pervasive developmental disorders or learning difficulties (especially of dysphasia and dyspraxia) * The presence of any neurological disorder or any other disorder affecting the central nervous system * Participants having any uncorrected auditory or visual deficits