Academisch Medisch Centrum - Universiteit Van Amsterdam (amc-uva)
Clinical trials sponsored by Academisch Medisch Centrum - Universiteit Van Amsterdam (amc-uva), explained in plain language.
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Poop pills show promise for gut disease
Disease control CompletedThis study tested whether transplanting stool from healthy donors into the gut of people with ulcerative colitis could reduce symptoms and inflammation. 85 adults received either donor or their own stool via a tube and enemas. The goal was to see if this treatment could help cont…
Phase: PHASE2 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated May 01, 2026 15:58 UTC
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New drug combo may help sickle cell patients avoid transplant rejection
Disease control CompletedThis study tested whether giving sickle cell patients azathioprine and hydroxyurea for three months before a stem cell transplant from a matched sibling donor could lower the risk of graft failure. Twenty adults aged 16 to 60 took part. The goal was to improve disease-free surviv…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Heart CT may spot clots missed by ultrasound in stroke patients
Diagnosis CompletedThis study looked at nearly 4,000 adults who had a stroke and also got a heart CT scan. The goal was to see how often the CT found blood clots in the heart that might have caused the stroke. Researchers compared CT results with standard echocardiograms to see which test works bet…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Diagnosis
Last updated May 01, 2026 15:57 UTC
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Tick bite study seeks to unlock natural immunity against ticks
Knowledge-focused CompletedThis study tested whether people can develop immunity to tick bites. Eleven volunteers with no prior tick exposure were bitten multiple times by laboratory-raised, disease-free ticks. Researchers measured tick feeding and signs of immune response to understand how the body reacts…
Phase: NA • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 01, 2026 20:12 UTC
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Global experts unite to clear the air on ICU breathing tube care
Knowledge-focused CompletedThis study brought together 35 healthcare experts from around the world to agree on the best ways to clear mucus from the airways of critically ill patients who are on breathing machines. The goal was to create clear, shared guidelines for treatments like humidification, inhaled …
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Brain clock may play role in diabetes risk
Knowledge-focused CompletedThis study looked at how the brain's central clock (the suprachiasmatic nucleus) works in people with different stages of insulin resistance. Researchers used advanced brain scans to measure clock activity in 28 obese adults, including those with normal insulin sensitivity, insul…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Robot vs. nurse: can a machine track urine better?
Knowledge-focused CompletedThis study tested whether an automated device called FlowSure can measure urine output more accurately than the usual manual method in hospitalized patients with a urinary catheter. 75 adults took part, and researchers compared the two methods over 8-hour and 24-hour periods. The…
Phase: NA • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Dutch study tracks COVID-19 drugs in real world to find who benefits most
Knowledge-focused CompletedThis study followed over 1,100 adults in the Netherlands who received monoclonal antibodies or antiviral pills for COVID-19. Researchers collected blood samples and nasal swabs over 90 days to measure how the virus and the body's immune response changed during treatment. The goal…
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Can a simple breathing machine tweak save lungs during surgery?
Knowledge-focused CompletedThis study tested whether using a personalized breathing machine setting during open abdominal surgery could prevent lung complications like pneumonia or respiratory failure. Over 1,400 adults at risk for lung problems took part. The approach aimed to avoid high pressure on the l…
Phase: NA • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC