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New tissue sampling method could boost gut disease research

NCT ID NCT06333093

First seen Jan 16, 2026 · Last updated Jun 23, 2026 · Updated 19 times

Summary

This study tested a technique called cold snare to collect larger pieces of tissue from the duodenum during a routine endoscopy. Researchers wanted to see if these samples were good enough for detailed analysis, including single cell RNA sequencing. The study involved 13 people already scheduled for an upper GI endoscopy. The goal was to improve tissue collection for future research on duodenal diseases.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Amsterdam UMC

    Amsterdam, North Holland, 1105 AZ, Netherlands

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could improve how doctors collect and analyze duodenal tissue, aiding future studies on duodenal diseases.

What could go wrong

This is a very small, completed study with only 13 participants, so results may not apply widely. It focused on tissue quality, not treatment.

Conditions

The condition(s) this trial relates to.

duodenal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.