New tissue sampling method could boost gut disease research

NCT ID NCT06333093

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a technique called cold snare to collect larger pieces of tissue from the duodenum during a routine endoscopy. Researchers wanted to see if these samples were good enough for detailed analysis, including single cell RNA sequencing. The study involved 13 people already scheduled for an upper GI endoscopy. The goal was to improve tissue collection for future research on duodenal diseases.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could improve how doctors collect and analyze duodenal tissue, aiding future studies on duodenal diseases.
What could go wrong
This is a very small, completed study with only 13 participants, so results may not apply widely. It focused on tissue quality, not treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Amsterdam UMC

    Amsterdam, North Holland, 1105 AZ, Netherlands