Academisch Medisch Centrum - Universiteit Van Amsterdam (amc-uva)

This study tests whether adding intravenous immunoglobulin (IVIg) to standard steroid treatment early in myositis leads to faster improvement and prevents long-term disability. About 44 adults with recent-onset myositis (less than 12 months) will receive either steroids plus IVIg…

This study tests a new procedure that uses gentle electric pulses to regenerate the lining of the small intestine in people with type 2 diabetes. The goal is to help them stop taking insulin while using a diabetes medication called semaglutide. The trial involves 32 adults and co…

This study tests whether a prescription fish oil drug (icosapent ethyl) can slow the buildup of calcium in the aortic valve, which causes narrowing and heart strain. About 110 adults over 50 with mild to moderate aortic stenosis will take the drug or a placebo for several months.…

This study tests a new device called Endosign that collects tissue samples from the esophagus through the mouth, without needing a full endoscopy. The goal is to see if this simpler method can reliably detect Barrett's esophagus, a condition that can lead to esophageal cancer. Ab…

This study tests a therapy called imagery rescripting in 8 people with early psychosis. The goal is to see if it can improve core beliefs, wellbeing, and self-esteem by helping patients change upsetting mental images. Participants receive 4-6 therapy sessions over a few weeks and…

This study looks at how combining blood tests (proteomics and genomics) with CT scans can help predict the worsening of heart artery disease. It involves 310 adults aged 50-75 who have early signs of artery buildup but no symptoms. The goal is to better understand who is at risk …