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Could a mouth swab replace endoscopy for Barrett's esophagus?

NCT ID NCT07490340

First seen Mar 27, 2026 · Last updated Apr 30, 2026 · Updated 6 times

Summary

This study tests a new device called Endosign that collects tissue samples from the esophagus through the mouth, without needing a full endoscopy. The goal is to see if this simpler method can reliably detect Barrett's esophagus, a condition that can lead to esophageal cancer. About 60 adults with Barrett's esophagus will try the device during their regular care. If it works well, it could make monitoring easier and less costly for patients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Amsterdam University Medical Centre, loc. VUmc

    Amsterdam, North Holland, 1081HV, Netherlands

Conditions

Explore the condition pages connected to this study.