ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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Major study aims to settle debate on best Barrett's esophagus treatment
Disease control Recruiting nowThis study compares two standard approaches for Barrett's esophagus with low-grade dysplasia: regular monitoring with biopsies (surveillance) versus procedures to remove or burn away abnormal cells (endoscopic therapy). The goal is to determine which method is safer and more effe…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 01, 2026 14:35 UTC
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New drug combo shows promise in advanced stomach cancer trial
Disease control Recruiting nowThis study tests a new medicine (PF-08634404) plus chemotherapy in people with advanced stomach, gastroesophageal junction, or esophageal cancer that has not been treated before. The goal is to see if the new combination works better than current standard treatment (nivolumab plu…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New drug combo tested for tough cancers
Disease control Recruiting nowThis early-stage study tests a new drug called sigvotatug vedotin, alone or with other cancer drugs, in people with advanced solid tumors like lung, head and neck, and breast cancers. The main goal is to check safety and find the right dose. About 1,000 participants will be enrol…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Could a bile acid blocker stop esophageal cancer before it starts?
Prevention Recruiting nowThis study tests whether obeticholic acid can prevent cancer in people with Barrett's esophagus, a condition that raises the risk of esophageal cancer. The drug works by reducing damage from bile acids that flow back into the esophagus. About 30 adults with Barrett's esophagus wi…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Apr 29, 2026 15:01 UTC