ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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New drug combo shows promise for tough cancers
Disease control Recruiting nowThis early-stage study tests a new drug called sigvotatug vedotin, alone or with other cancer drugs, in people with advanced solid tumors like lung, head and neck, and breast cancer. The goal is to find a safe dose and check for side effects. About 1,000 participants will take pa…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Major study aims to settle debate: monitor or treat precancerous esophagus?
Disease control Recruiting nowThis study looks at two common ways to manage Barrett's esophagus with low-grade dysplasia: regular check-ups with biopsies (surveillance) or procedures to remove or burn away abnormal cells (endoscopic therapy). The goal is to see which approach better prevents cancer while avoi…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 12, 2026 12:07 UTC
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New combo therapy aims to fight advanced stomach cancer
Disease control Recruiting nowThis study tests a new medicine (PF-08634404) given with chemotherapy to people with advanced stomach, gastroesophageal junction, or esophageal cancer that has not been treated before. The goal is to see if the new combination works better than the current standard treatment (niv…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 11, 2026 12:10 UTC
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Could a bile acid blocker stop Barrett's esophagus from turning into cancer?
Prevention Recruiting nowThis study tests whether obeticholic acid can prevent Barrett's esophagus from progressing to esophageal cancer. Barrett's esophagus is a condition where the lining of the food pipe changes due to stomach acid and bile exposure, raising cancer risk. The drug works by reducing bil…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Jun 15, 2026 18:54 UTC