ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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Major study aims to settle debate: monitor or treat precancerous esophagus?
Disease control Recruiting nowThis study looks at two common ways to manage Barrett's esophagus with low-grade dysplasia—a condition where the esophagus lining has abnormal cells that rarely turn into cancer. One approach is regular check-ups with biopsies (surveillance), and the other is a procedure to remov…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Apr 29, 2026 00:51 UTC
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New drug combo shows promise in early cancer trial
Disease control Recruiting nowThis early-stage trial tests a new drug called sigvotatug vedotin, alone or with other cancer treatments, in people with advanced solid tumors like lung, head and neck, and breast cancer. The main goal is to check safety and find the right dose. Around 1,000 participants will be …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Disease control
Last updated Apr 29, 2026 00:51 UTC
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New combo therapy aims to fight tough stomach cancers
Disease control Recruiting nowThis study tests a new medicine (PF-08634404) combined with chemotherapy for people with advanced stomach, gastroesophageal junction, or esophageal cancer that has not been treated before. The trial has two parts: first to check safety and response, then to compare the new combo …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Apr 29, 2026 00:50 UTC
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Could a bile acid blocker stop esophageal cancer before it starts?
Prevention Recruiting nowThis study tests whether obeticholic acid can prevent cancer in people with Barrett's esophagus, a condition that raises the risk of esophageal cancer. The drug works by reducing damage from bile acids that flow back into the esophagus. About 30 adults with Barrett's esophagus wi…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Prevention
Last updated Apr 29, 2026 00:51 UTC