ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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New drug combo aims to outperform standard immunotherapy in stomach cancer
Disease control OngoingThis phase 3 study tests whether a new combination of two immunotherapy drugs (domvanalimab and zimberelimab) plus chemotherapy works better than the current standard (nivolumab plus chemotherapy) for people with advanced stomach, gastroesophageal junction, or esophageal cancer t…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Arcus Biosciences, Inc. • Aim: Disease control
Last updated Jun 22, 2026 12:03 UTC
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Immunotherapy combo shows promise in esophageal cancer trial
Disease control OngoingThis study tests whether adding the immunotherapy drug durvalumab to standard chemoradiation is safe and effective for people with esophageal or gastroesophageal junction cancer. About 64 participants will receive initial chemotherapy, then durvalumab with chemoradiation, followe…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 22, 2026 11:57 UTC
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Swallow a sponge to check for esophageal cancer?
Diagnosis OngoingThis study tests a device called Endosign, which is a sponge on a string that patients swallow to collect cells from the esophagus. The goal is to see if this simple, non-sedation method can provide good enough samples to replace regular endoscopies for monitoring Barrett's esoph…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Diagnosis
Last updated Jun 22, 2026 11:57 UTC
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Cancer biobank study aims to unlock secrets of immunotherapy resistance
Knowledge-focused TerminatedThis observational study collects blood and tumor tissue samples from people with gastroesophageal cancer to study genetic changes that may cause resistance to immunotherapy. It does not involve any treatment or experimental drugs. The goal is to identify new targets for future i…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:52 UTC