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New chemo combo aims to shrink tumors with fewer nerve problems

NCT ID NCT03764553

First seen Apr 15, 2026 · Last updated May 24, 2026 · Updated 6 times

Summary

This study tests three different chemotherapy combinations in 320 people with advanced esophageal or stomach cancer that has not been treated before. The goal is to find which combination works best to keep the cancer from growing while causing the least nerve damage. Participants will receive one of the three treatments, and researchers will compare how long the cancer stays under control and how many side effects occur.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Academic Medical Center, Medical Oncology

    Amsterdam, 1100 DD, Netherlands

  • Admiraal de Ruijter Ziekenhuis

    Goes, 4460 AA, Netherlands

  • Amphia Ziekenhuis

    Breda, 4818 CK, Netherlands

  • Bravis ziekenhuis locatie Roosendaal

    Roosendaal, 4708 AE, Netherlands

  • Canisius Wilherlmina ziekenhuis

    Nijmegen, Netherlands

  • Catherina Ziekenhuis

    Eindhoven, Netherlands

  • Dijklander ziekenhuis

    Hoorn, Netherlands

  • Elkerliek ziekenhuis

    Helmond, Netherlands

  • Flevoziekenhuis

    Almere Stad, Netherlands

  • Haaglanden Medisch Centrum

    The Hague, Netherlands

  • Ikazia ziekenhuis

    Rotterdam, Netherlands

  • Isala Klinieken

    Zwolle, Netherlands

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, 5223 GZ, Netherlands

  • Laurentius Ziekenhuis

    Roermond, Netherlands

  • Leids Universitair Medisch Centrum

    Leiden, Netherlands

  • Maasstadziekenhuis

    Rotterdam, Netherlands

  • Meander MC

    Amersfoort, Netherlands

  • Medisch Centrum Leeuwarden

    Leeuwarden, Netherlands

  • Nij Smellinghe

    Drachten, Netherlands

  • Radboud Universitair Medisch Centrum

    Nijmegen, Netherlands

  • Reinier de Graaf Gasthuis

    Delft, 2625 AD, Netherlands

  • Rijnstate Ziekenhuis

    Arnhem, 6815 AD, Netherlands

  • Rivierenland Ziekenhuis

    Rotterdam, Netherlands

  • Sint Antonius Ziekenhuis

    Nieuwegein, Netherlands

  • Sint Jansdal

    Harderwijk, Netherlands

  • Spaarne Gasthuis

    Hoofddorp, Netherlands

  • Tergooi ziekenhuizen

    Hilversum, Netherlands

  • Treant Zorggroep

    Emmen, Netherlands

  • Treant zorggroep

    Hoogeveen, 7909 AA, Netherlands

  • UMCU

    Utrecht, 3508 GA, Netherlands

  • VieCurie

    Roermond, 6043 CV, Netherlands

  • Ziekenhuis Gelderse Vallei

    Ede, Netherlands

  • Ziekenhuisgroep Twente

    Almelo, Netherlands

  • Zuyderland Medisch Centrum

    Geleen, Netherlands

Conditions

Explore the condition pages connected to this study.