TYPE 1 DIABETES MELLITUS
Clinical trials for TYPE 1 DIABETES MELLITUS explained in plain language.
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New tech tool helps seniors with diabetes avoid dangerous low blood sugar
Disease control CompletedThis study tested whether a continuous glucose monitor (CGM) combined with a diabetes management platform (DMP) can help older adults (65+) with type 1 diabetes reduce low blood sugar episodes. The DMP automatically sends glucose and insulin data to a system that gives dose adjus…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Joslin Diabetes Center • Aim: Disease control
Last updated May 26, 2026 08:02 UTC
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Community helpers may boost diabetes control in kids
Disease control CompletedThis study tested whether adding a community health worker to the care team helps children with type 1 diabetes improve blood sugar control and reduce hospital visits. 84 children with type 1 diabetes for over a year and with recent high blood sugar or hospital visits took part. …
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 26, 2026 08:01 UTC
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No-Carb-Count insulin tool tested in small diabetes trial
Disease control CompletedThis small study tested a new tool called InsuLearn that helps people with type 1 diabetes calculate their insulin doses without needing to count carbohydrates. Seven adults on multiple daily injections used the tool for a day, and researchers compared their blood sugar control t…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University of Virginia • Aim: Disease control
Last updated May 26, 2026 07:59 UTC
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Smart pump and CGM combo could ease diabetes management
Disease control CompletedThis study tested a hybrid closed loop system that combines a Tandem insulin pump with a Dexcom continuous glucose monitor to automatically adjust insulin delivery in adults with type 1 diabetes. Thirty participants used the system for a year to see if it improved blood sugar con…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: NHS Lothian • Aim: Disease control
Last updated May 26, 2026 07:57 UTC
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Teens' diabetes tech tested: which system handles surprise meals best?
Disease control CompletedThis study tested two advanced insulin pumps (Medtronic 780G and Tandem t:slim X2) in 20 teenagers with type 1 diabetes. The goal was to see how well each system manages blood sugar after unannounced meals with different amounts of carbs. Results will help improve diabetes care a…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University of Catania • Aim: Disease control
Last updated May 26, 2026 07:54 UTC
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App-Based learning boosts diabetes control in teens
Disease control CompletedThis study tested whether a mobile app-based education program helps teenagers with type 1 diabetes manage their condition better. 96 teens aged 12-18 were split into two groups: one used the app for diabetes education, the other received standard care. The goal was to see if the…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Deniz Akkaya Balcı • Aim: Disease control
Last updated May 26, 2026 07:54 UTC
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Hope for kidneys: new drug targets diabetes damage
Disease control CompletedThis study tested whether the drug finerenone can slow the worsening of chronic kidney disease in people with type 1 diabetes. About 241 adults took either finerenone or a placebo pill for 6 months, along with their usual treatments. Researchers measured changes in urine protein …
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE3 • Sponsor: Bayer • Aim: Disease control
Last updated May 26, 2026 07:53 UTC
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Experimental kidney cell therapy shows promise for diabetic patients
Disease control CompletedThis study tested a new treatment called REACT (rilparencel) for people with type 1 or type 2 diabetes who also have chronic kidney disease. The treatment uses a person's own kidney cells to try to slow down kidney damage. 53 adults aged 30 to 80 took part, and the study looked a…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE2 • Sponsor: Prokidney • Aim: Disease control
Last updated May 26, 2026 07:26 UTC
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Smart pen cap could help tame type 1 diabetes
Disease control CompletedThis study tested a device called Cap INSULCLOCK, which attaches to insulin pens and automatically records injections. It aims to help adults with type 1 diabetes better manage their blood sugar levels by tracking insulin use, glucose, food, and activity. 42 participants used eit…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE4 • Sponsor: Fernando Sebastián Valles • Aim: Disease control
Last updated May 26, 2026 07:25 UTC
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Stem cell therapy shows promise for controlling type 1 diabetes
Disease control CompletedThis study tested a stem cell treatment called PROCHYMAL in 63 people recently diagnosed with type 1 diabetes. The goal was to see if the treatment could safely help the body keep making some of its own insulin, reducing the need for injected insulin. Participants received multip…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE2 • Sponsor: Mesoblast, Inc. • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Smart pancreas system aims to stop exercise-induced low blood sugar in type 1 diabetes
Disease control CompletedThis study tested whether an artificial pancreas system with exercise recognition could prevent low blood sugar (hypoglycemia) during and after moderate exercise in adults with type 1 diabetes. Fifteen participants used two different versions of the system over several months. Th…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Marc Breton • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Can a Vaccine-Like shot retrain the immune system to stop diabetes?
Disease control CompletedThis early-phase study tested a new treatment called IBC with MAS-1 adjuvant in 21 adults recently diagnosed with type 1 diabetes. The goal was to see if it is safe and can retrain the immune system to stop attacking the pancreas, potentially preserving natural insulin production…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: PHASE1 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New insulin system helps kids with diabetes stay in healthy range
Disease control CompletedThis study looked at how well the TouchCare Nano automated insulin delivery system works for children and teens with type 1 diabetes in everyday life. Researchers tracked 76 participants over six months to see if the system helped them keep blood sugar in a healthy range and redu…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: University of Campania Luigi Vanvitelli • Aim: Disease control
Last updated May 19, 2026 11:46 UTC
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New injection map could help diabetics avoid painful lumps and improve sugar control
Disease control CompletedThis study tested a new tool—a visual injection site map—to help people with diabetes rotate their insulin injection spots properly. 170 adults who had been on insulin for at least six months took part. Half received the map and instructions, while the other half got standard ver…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Helwan University • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Cold and vibration devices ease insulin injection pain in children
Symptom relief CompletedThis study tested two small devices—Coolsense (cold only) and Buzzy (cold plus vibration)—to see if they reduce pain and anxiety in children aged 6–12 with type 1 diabetes during insulin injections. 90 children were split into three groups: one used Coolsense, one used Buzzy, and…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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New video program eases parents' fear of kids' low blood sugar
Symptom relief CompletedThis study tested a home video-based telemedicine program called REDCHiP to help parents of young children (ages 2-6) with type 1 diabetes reduce their fear of hypoglycemia (low blood sugar). The program aimed to lower parental stress and improve children's blood sugar control. T…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Nemours Children's Clinic • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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What do people with type 1 diabetes think about artificial pancreas systems?
Knowledge-focused CompletedThis study surveyed 166 adults with type 1 diabetes to understand their choices and experiences with hybrid closed-loop (artificial pancreas) technology. The goal was to learn what factors influence their decision to use these systems and how satisfied they are with them. No trea…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated May 26, 2026 08:02 UTC
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Sugar substitutes under scrutiny: new study probes impact on young diabetics
Knowledge-focused CompletedThis study explored how non-caloric artificial sweeteners (like those in diet drinks) affect body fat, muscle, and blood sugar control in young people aged 5-17 with type 1 diabetes. Researchers measured body composition and ran blood tests, and asked participants about their die…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: Medical College of Wisconsin • Aim: Knowledge-focused
Last updated May 26, 2026 08:01 UTC
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Massive study hunts for hidden triggers of type 1 diabetes in children
Knowledge-focused CompletedThis study followed over 8,600 children from birth to identify what in the environment—like viruses or diet—might trigger type 1 diabetes in those with a genetic risk. Researchers collected blood and stool samples to track when the immune system first attacks the pancreas. The go…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated May 26, 2026 07:26 UTC
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Period power: new study reveals menstrual Cycle's impact on diabetes control
Knowledge-focused CompletedThis study examined how the menstrual cycle affects insulin sensitivity and blood sugar control in 77 women with type 1 diabetes. Researchers analyzed data from continuous glucose monitors and insulin pumps to compare the follicular and luteal phases. The goal is to help women be…
Matched conditions: TYPE 1 DIABETES MELLITUS
Sponsor: DCB Research AG • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC
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New program helps teens with diabetes speak up for better health
Knowledge-focused CompletedThis study tested a program to help teens and young adults (ages 17-23) with type 1 diabetes improve how they talk to doctors when moving from pediatric to adult care. 52 participants were split into two groups: one got communication and transition training, the other got standar…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Children's National Research Institute • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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Fat clues in diabetic pregnancies: can they predict bigger babies?
Knowledge-focused CompletedThis study looked at 186 pregnant women with type 1 or type 2 diabetes to understand how fats (lipids) in the mother's and baby's blood relate to birth weight. Even when blood sugar is well-controlled, babies of diabetic mothers are often larger than average, which can cause deli…
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC
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Teens with type 1 diabetes: counting fat and protein may improve blood sugar control after meals
Knowledge-focused CompletedThis study looked at 11 teens with type 1 diabetes to see how high-fat, high-protein meals affect their blood sugar. Researchers tested different ways of counting nutrients to adjust insulin doses. The goal was to find better methods for managing blood sugar after eating.
Matched conditions: TYPE 1 DIABETES MELLITUS
Phase: NA • Sponsor: Cumhuriyet University • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC