TYPE 1 DIABETES MELLITUS

This study tested a hybrid closed-loop insulin system for adults with type 1 diabetes. The system combines a Tandem insulin pump with a Dexcom G6 continuous glucose monitor to automatically adjust background insulin. The goal was to see if this technology improves blood sugar con…

This early-stage study tested whether an experimental vaccine called MER3101 is safe for people with recent-onset type 1 diabetes. Twenty-one adults received injections to try to shift their immune system away from attacking insulin-producing cells. All participants continued the…

This study tested whether a special mobile app could help teenagers with Type 1 diabetes manage their condition better. Researchers compared 96 teens who used the educational app against teens who received standard medical care. They measured if the app improved the teens' confid…

This small study tested if a smartphone app could simplify mealtime insulin dosing for adults with type 1 diabetes. Instead of counting carbs, participants used the app to estimate meals. The goal was to see if this simpler method could help control blood sugar levels as well as …

This study tested whether adding the medication finerenone to standard care could better protect kidney function in adults with both chronic kidney disease and type 1 diabetes. Researchers compared finerenone against a placebo (inactive pill) in 241 participants over 6 months of …

This study tested whether injections of a patient's own processed kidney cells (called REACT) could safely slow the worsening of kidney function in people with diabetes and chronic kidney disease. It involved 53 participants who received up to two injections into their kidneys an…

This study tested whether stem cell injections could protect the body's insulin-producing cells in people recently diagnosed with type 1 diabetes. Researchers gave 63 participants either the stem cell treatment or a placebo to see if it could slow or stop the immune system's atta…

This study tested whether a smart cap that attaches to insulin pens helps adults with type 1 diabetes better control their blood sugar. The cap automatically records insulin doses and connects to a phone app to track glucose, food, and activity. Researchers compared 42 patients u…

This study tested two different automated insulin pumps in teenagers with type 1 diabetes to see which one was better at managing blood sugar after eating a meal without warning. Twenty teens tried both the Medtronic 780G and Tandem t:slim X2 pumps, eating different types of surp…

This study tested whether adding a trained community health worker to a child's diabetes care team could help improve their blood sugar control. It involved 84 children with poorly controlled type 1 diabetes. The community worker provided personalized support for one year, helpin…

This study tested two simple devices to see if they could make insulin injections less painful and frightening for children with Type 1 diabetes. Researchers compared a cold-only device and a combined cold-and-vibration device against standard injection care in 90 children aged 6…

This study aimed to understand if non-calorie artificial sweeteners, commonly used by people with type 1 diabetes, are linked to body composition and blood sugar control. Researchers measured body fat, muscle, and blood markers in 21 youth with type 1 diabetes and asked detailed …

This study aimed to understand how the protein and fat in a meal, not just carbohydrates, affect blood sugar levels in teenagers with type 1 diabetes. Researchers fed 11 teens different test meals and monitored their blood sugar for six hours to see if adjusting insulin for prote…

This study looked at how different phases of the menstrual cycle affect blood sugar control and insulin needs in women with type 1 diabetes. Researchers analyzed anonymous data from 77 women who used continuous glucose monitors and insulin devices. The goal was to understand thes…

This study aimed to understand why babies born to mothers with diabetes are often larger, even when blood sugar is well-controlled. Researchers followed 186 pregnant women, including those with type 1 or type 2 diabetes and those without, to see if specific fats in the mother's a…

This study aimed to discover what in the environment—like viruses, diet, or stress—might trigger type 1 diabetes in children who are genetically at risk. Researchers followed over 8,600 newborns with a family history of diabetes or high-risk genes from infancy, collecting health …