TYPE 1 DIABETES MELLITUS

This study is testing a small, implantable device called the Cell Pouch that holds insulin-producing cells for people with severe Type 1 diabetes. The goal is to see if this 'biohybrid organ' is safe and can help reduce dangerous low blood sugar episodes and improve blood sugar c…

This study is testing whether giving two immune-suppressing drugs (rituximab-pvvr followed by abatacept) is better than one drug alone for people recently diagnosed with type 1 diabetes. The main goal is to see if the combination helps the body preserve its own ability to make in…

This early-stage study is testing the safety of a personalized vaccine made from a patient's own immune cells. The goal is to teach the immune system to stop attacking the insulin-producing cells in the pancreas. Six adults with recently diagnosed type 1 diabetes will receive the…

This study is testing whether Swedish massage or yoga exercises can help children with type 1 diabetes better control their blood sugar levels. Researchers are comparing these two stress-reduction techniques in 50 children aged 6-12 who live in Cairo. The goal is to see if either…

This study is testing whether a daily cholesterol-lowering pill called fenofibrate can slow down or prevent eye damage in adults with Type 1 diabetes. It involves about 450 participants who already have early signs of diabetic eye disease. The goal is to see if taking the pill fo…

This study is testing whether an experimental drug called brivekimig can help protect the body's remaining insulin-producing cells in people recently diagnosed with type 1 diabetes. The goal is to see if the drug can slow the disease's progression and reduce the amount of insulin…

This study is testing whether a daily probiotic supplement can help control type 1 diabetes in children and teens recently diagnosed. Researchers want to see if changing gut bacteria can reduce harmful inflammation and potentially slow the loss of the body's insulin-producing cel…

This study is testing whether transplanting insulin-producing cells from donors into people with Type 1 diabetes is a safe and effective treatment. The procedure aims to help patients achieve better blood sugar control and potentially become independent from daily insulin injecti…

This Phase 3 trial is testing whether injections of an investigational drug called Diamyd, given directly into a lymph node, can help preserve the body's remaining insulin-producing cells in people recently diagnosed with type 1 diabetes. The study is for adolescents and young ad…

This study is testing a smartphone app called Diabetes M to see if it helps people with type 1 diabetes calculate their mealtime insulin doses better than their usual method. About 30 adults who use insulin pumps or multiple daily injections will try the app for two weeks. Resear…

This study is testing whether a daily probiotic supplement can help people recently diagnosed with type 1 diabetes. Researchers want to see if the probiotic reduces harmful inflammation in the body and helps preserve the body's own ability to produce some insulin. The study invol…

This study is checking how well and how safely a wearable, automated insulin system works for children and teenagers with type 1 diabetes in their everyday lives. About 76 young people will use the system as part of their regular care for six months. Researchers will collect data…

This study is exploring whether a father's diabetes and weight can leave marks on his sperm that might influence his future children's health risks. Researchers are enrolling 40 overweight men with type 1 or type 2 diabetes to see if a 3-month lifestyle program focused on blood s…

This is a long-term observational study following people who were part of a major type 1 diabetes trial from the 1980s and 1990s. It tracks how early, intensive blood sugar control affects the development of serious complications like eye, kidney, and heart disease over many deca…