SPINAL CORD INJURY

This study tested whether repeated sessions of passive heating (like sitting in a warm room or bath) could improve inflammation, blood vessel function, and blood sugar control in people with spinal cord injury. Ten adults with stable spinal cord injury for over a year took part i…

This study tested an experimental drug called MT-3921 in 72 people with a recent severe spinal cord injury in the neck. Participants received either the drug or a placebo by IV over 6 months. The main goal was to see if the drug improves arm and hand muscle function better than p…

This study looked at whether combining electrical muscle stimulation with vitamin D pills could improve bone health in veterans with long-term spinal cord injury. Six participants received the treatment over 9 months, and researchers measured changes in bone structure using MRI a…

This study tested a new rehab approach for people with spinal cord injury. Ten participants received a combination of spinal cord stimulation (a device that sends electrical pulses to the spine) and a robotic exoskeleton (a wearable robot that helps with walking). The goal was to…

This study tested a biodegradable implant containing growth factors and nerve grafts in 10 people with complete spinal cord injuries. The implant was surgically placed at the injury site to encourage nerve regrowth. The main goals were to check safety and see if it could improve …

This study tested whether a single dose of zoledronic acid, a drug already used for osteoporosis, can prevent the rapid bone loss that often follows a spinal cord injury. Researchers measured bone density and strength in 60 adults who had recently lost the ability to walk. The go…

This study tested whether a bone-building drug (teriparatide) and whole-body vibration could help restore bone lost after spinal cord injury. 60 adults with chronic SCI and low bone density received one or both treatments for 12 months. The goal was to see if these approaches cou…

This study tested a combination of testosterone therapy and a special type of electrical stimulation to rebuild leg muscle in 12 people with spinal cord injury. Participants had severe muscle loss because nerves to their legs were damaged. The goal was to see if this approach cou…

This study tested whether a combination of two drugs, dextromethorphan (taken by mouth) and lidocaine (given through a vein), can reduce nerve pain in people with spinal cord injury. 26 adults with long-term pain took part in a carefully controlled trial where neither they nor th…

This study tested a new online program to help people with spinal cord injury cope better and improve their mental health. Twelve adults with spinal cord injury who had mild to moderate anxiety or depression took part in eight weekly online group sessions led by a nurse. The main…

This study tested simple, low-cost devices to help people with spinal cord injury walk on a treadmill. Nineteen participants with injuries between the neck and mid-back used the devices, and researchers measured changes in walking speed and leg movement. The goal was to make trea…

This study looked at whether keeping blood pressure higher (85-90 mmHg) for a week after a spinal cord injury helps people recover movement and feeling better than standard care (65-70 mmHg). 94 adults with new spinal cord injuries took part. The goal was to see if a higher blood…

This small study tested whether combining virtual walking (a computer simulation) with a gentle brain stimulation technique (tDCS) could help ease chronic nerve pain in people with spinal cord injury. Four participants tried the treatment for 10 sessions over two weeks. The main …

This study tested whether daily electrical stimulation of the buttock muscles can help people with chronic spinal cord injury. Over six months, 30 participants received 35-minute stimulation sessions each day. Researchers measured changes in muscle size and sitting pressure to se…

This study tested three doses of dextromethorphan (a cough suppressant) against a placebo to see if it could reduce central neuropathic pain in people with spinal cord injury. 26 adults with chronic pain took part in a crossover trial where each person received all doses in a ran…

This study tested a non-invasive method to help regulate blood pressure in veterans with spinal cord injury who have chronically low blood pressure. Researchers placed electrodes on the skin over the spine and adjusted the stimulation to find the best settings for raising blood p…

This study tested whether a high-intensity exercise program, run by Doctor of Physical Therapy students, helps people with neurologic disabilities (like cerebral palsy, stroke, or spinal cord injury) move better in daily life. Fifteen participants aged 8 to 99 completed the progr…

This study tested a 7-week program that teaches people with spinal cord injury and chronic pain how to manage their pain using brain-based techniques and self-care tools. Participants attended group sessions and one-on-one coaching to learn about pain science, movement, and relax…

This study tested whether a drug called KAI-1678 can reduce pain in people with spinal cord injury. Five adults with long-term spinal cord injury and ongoing nerve pain received either the drug or a placebo. The goal was to see if the drug lowered pain intensity within 6 hours.

This small pilot study tested two ways to stimulate the spinal cord (surface or implanted) combined with a robotic exoskeleton to help people with spinal cord injury walk. Four men with complete motor paralysis below the chest took part. The goal was to see if these approaches im…

This study looked at whether community-based wellness programs can improve health, quality of life, and care experience while lowering costs for adults with disabilities like spina bifida, cerebral palsy, spinal cord injury, or traumatic brain injury. Researchers enrolled 130 peo…

This study tested a new robotic device called REACTION that helps with walking and balance training. Seven people with stroke or spinal cord injury tried the device in two sessions, doing walking and balance tasks. The main goal was to see if the device is practical to use, not t…

This study looked at how the brain sends signals to muscles after a spinal cord injury. Researchers tested 120 people with chronic neck-level injuries to map brain activity and measure hand and arm function. The goal was to gather knowledge that could lead to better therapies for…

This study looked at how a robotic body-weight support system called 'the FLOAT' changes the way people with incomplete spinal cord injury perform everyday tasks like walking, standing up, and climbing stairs. About 65 participants were invited for a single visit to measure their…

This study looked at how thinking difficulties appear in the brains of people with spinal cord injury. 54 adults (with and without spinal cord injury) completed thinking tasks inside an MRI scanner. The goal was to understand brain activity related to focus and word fluency, not …

This study looked at 116 adults with spinal cord injury to see if ultrasound measurements of bladder wall thickness match standard bladder function tests. The goal was to find a simpler, non-invasive way to check bladder health. Results may help doctors monitor bladder issues wit…

This study aimed to find specific molecules in the body that are linked to better recovery after a spinal cord injury. Researchers collected blood and other samples from 106 adults with recent spinal cord injuries at three key time points: before rehab, after rehab, and one year …

This study looked at how people with spinal cord injury improve their walking ability during robot-assisted gait training. Ten participants used a robotic device called Lokomat to help them walk, and their progress was measured before, during, and after the training, plus one mon…

This study looked at how spinal cord injury affects women's thoughts and experiences about having children, birth control, and pregnancy. Researchers surveyed 70 women with spinal cord injury to understand their needs and challenges. The goal was to gather information to help imp…