SPINAL CORD INJURY

This study will test a self-balancing robotic exoskeleton called XoMotion-R in 16 people with spinal cord injury (SCI) who have some movement in their legs. The device allows users to walk hands-free, which may help those who cannot use crutches or walkers. Researchers want to se…

This study tests whether walking in a robotic exoskeleton combined with mild electrical stimulation of the spinal cord can help rebuild muscle and bone in people with long-term spinal cord injury. 24 non-walking participants will be assigned to either active or sham stimulation d…

This early-stage study tests whether a concentrated dose of a patient's own growth factors can help repair spinal cord damage. Ten adults with traumatic spinal cord injuries will receive the treatment, and researchers will track changes in their motor function. The goal is to fin…

This early-stage trial tests whether transplanting a patient's own nose cells into the spinal cord, combined with intensive exercise, is safe and feasible for people with chronic spinal cord injury. Up to 30 participants will receive the cell transplant and a 32-week rehab progra…

This study tests a new treatment called XS228, made from stem cells, to help repair nerve damage in people who had a spinal cord injury 2 to 12 weeks ago. About 60 adults with severe but incomplete paralysis will receive either a single injection of XS228 into their spinal fluid …

This study tests whether adding functional electrical stimulation (FES) to standard rehab can reduce muscle stiffness, strengthen legs, and improve walking and daily function in people with paraplegia. About 40 adults with spinal cord injury will be randomly assigned to either re…

This study tests whether adding a gentle electrical stimulation to the spinal cord during walking therapy can improve leg movement in people who had a spinal cord injury within the last 6 months. The therapy aims to boost the brain and spinal cord's natural ability to rewire itse…

This study will test a non-invasive device called the Spatial StimeMD (SSMD) in 120 adults aged 18-80 who have had a stroke, traumatic brain injury, spinal cord injury, or peripheral nerve damage within the past 2 years. The device uses gentle stimulation to help improve arm and …

This study tests an online program called EmpowerSpine for people with spinal cord injury who have chronic pain. The program teaches pain biology, daily coping strategies, and resilience skills. Researchers want to find out which parts of the program—like guidance from a clinicia…

This pilot study tests whether a small device that gently stimulates a nerve in the ear can safely reduce nerve pain in people with spinal cord injury. Thirty-two adults will use the device at home for 30 days, and researchers will measure pain levels, inflammation, and quality o…

This study tests a new approach to improve walking in people with chronic spinal cord injury. It combines loud sounds, mild electrical stimulation, and walking practice to activate hidden nerve pathways. The goal is to increase walking speed and leg strength. The study involves 2…

This study tests if a special arm-crank exercise (eccentric training) is better than standard strength training for people recovering from a spinal cord injury. Twenty adults in early rehab will do 20 sessions over 12 weeks. Researchers will measure changes in upper body strength…

This study aims to create a patient empowerment program for 30 veterans with spinal cord injury or disease and neurogenic bladder who have had at least one urinary tract infection in the past year. The program gives them tools to discuss bladder symptoms with their doctors and av…

This study tests whether a home-based digital rehab program, combined with a non-invasive spinal stimulation device, can safely improve arm and hand function in people with chronic tetraplegia. Nine adults with spinal cord injury will use a mobile app-guided exercise program and …

This study tests a new AI-driven system that uses mild electrical stimulation on the back to help people with spinal cord injury walk better. Unlike current methods that use fixed settings, this system adjusts stimulation in real time based on muscle signals and movement. The stu…

This study looks at whether a type of talk therapy called Focused Acceptance and Commitment Therapy (FACT) can help people with spinal cord injury feel better emotionally and improve their quality of life. About 8 patients in the hospital for rehab will try the therapy and fill o…

This study tests whether an AI-powered mobile app can help people with spinal cord injury manage bowel problems better. About 34 adults will use the app to learn bowel care routines. The goal is to reduce bowel dysfunction scores, shorten bathroom time, and improve quality of lif…

This study tests a live, group tele-exercise program (TEEMS) for 200 adults with spinal cord injury. Participants will join online classes or watch pre-recorded videos for 8 weeks. The goal is to see if the live program improves exercise confidence, physical activity, and quality…

This study follows 16 people with overactive bladder due to spinal cord injury who received an experimental gene therapy called EG110A. Researchers will track side effects and how well the treatment works over five years. The goal is to understand the therapy's long-term safety a…

This study looks back at the medical records of 50 people with spinal cord injuries treated over the past five years. The goal is to learn more about what caused their injuries and what complications they faced, such as pressure sores, infections, or muscle stiffness. By sharing …

This study translates and tests a short questionnaire about bladder symptoms for Turkish-speaking adults with spinal cord injury or multiple sclerosis. Researchers will check if the Turkish version is accurate and reliable by comparing it to other surveys. The goal is to give doc…

This study looks at whether a home-based shoulder strength training program can improve shoulder health in people who use manual wheelchairs after a spinal cord injury. Forty participants will start training either 3 or 12 months after leaving rehab, doing exercises twice a week …

This study looks at how the Achilles tendon behaves during walking in people with spastic paresis caused by stroke or spinal cord injury, compared to healthy volunteers. Researchers will measure tendon stiffness, length, and volume using ultrasound and strength tests. The goal is…

This study aims to improve a mobile brain-computer interface (BCI) that lets people with paralysis control computers and touchscreen devices using only their thoughts. Researchers will test the system's accuracy and ease of use in 2 participants who are already part of a larger B…