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Shock therapy for paraplegia: new trial tests muscle zapping

NCT ID NCT07583576

Symptom relief Sponsor: Istanbul Medipol University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding Functional Electrical Stimulation (FES) to standard rehab can reduce leg stiffness, build muscle strength, and improve walking in people with paraplegia. Forty adults with spinal cord injury will be split into two groups: one gets rehab alone, the other gets rehab plus FES. After 8 weeks, researchers will compare changes in spasticity, strength, and mobility.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Functional Electrical Stimulation (FES)
What this could lead to
If it works, this could offer a simple, non-drug way to reduce muscle stiffness and improve walking and daily function for people with paraplegia.
What could go wrong
This is a small, early-stage trial with only 40 participants. The results may not apply to everyone, and the benefits may be modest or not last long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jul 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants will be included in the study if they meet all of the following criteria: * Aged between 18 and 65 years * Diagnosed with spinal cord injury resulting in paraplegia (traumatic or non-traumatic etiology) * Classified as ASIA Impairment Scale C or D * Medically stable condition * Presence of lower extremity spasticity (Modified Ashworth Scale ≥ 1) * Ability to understand and follow simple instructions * Willingness to participate and provide informed consent Exclusion Criteria: * Participants will be excluded if they present any of the following conditions: * Presence of cardiac pacemaker or implanted electrical device * Severe cognitive impairment or communication difficulties preventing participation * Active infection or systemic inflammatory condition * Severe lower extremity contractures or deformities limiting movement * Dermatological conditions or open wounds preventing FES application * History of severe autonomic dysreflexia triggered by electrical stimulation * Uncontrolled medical conditions that may interfere with participation or safety

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Conditions

The condition(s) this trial relates to.

Muscle Spasticity paraplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neurorehabilitation Paraplegia Spasticity Spinal cord injury

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.