SPASTICITY

This early-stage study tests whether focused shockwave therapy can reduce arm and hand spasticity in people with spinal cord injury. Twelve participants will receive three weekly treatments, and researchers will measure changes in muscle stiffness, function, and quality of life. …

This study tests a new drug called IPN10200 for adults with arm muscle stiffness (spasticity) after a stroke or traumatic brain injury. The goal is to find the best dose that safely reduces stiffness and improves movement. About 240 people will receive either the new drug, a simi…

This study tests a procedure called cryoneurolysis, which uses cold to freeze specific nerves in the shoulder, to see if it relieves pain and improves movement in people with spasticity (muscle tightness) after stroke, brain injury, or multiple sclerosis. It compares the freezing…

This study looks at whether a mild, non-invasive stimulation on the back (like a light tap) can reduce muscle tightness (spasticity) in children with cerebral palsy. About 30 children aged 5 to 17 will do movement exercises and receive the stimulation to see if it helps their mus…

This study is testing a portable, wearable exoskeleton that can stretch the legs and assist with walking for people who have muscle stiffness (spasticity) due to a spinal cord injury. Ten veterans will try the device during leg stretches, treadmill walking, and overground walking…

This study tests whether a full-body stimulation suit used at home can reduce spasticity (muscle stiffness) and ataxia (poor coordination) in people with Multiple Sclerosis. About 70 participants will either use the suit for 6 weeks or continue their usual care. The goal is to se…

This study looks at how muscle stiffness (spasticity) appears in the arms and legs of people with multiple sclerosis and how it affects their daily life. Researchers will examine 75 adults with MS to classify different spasticity patterns and link them to quality of life. The goa…

This study is collecting information from 4,500 people who have had brain surgery for conditions like aneurysms, tumors, or epilepsy. The goal is to find out what factors help predict recovery, such as thinking skills and emotional health. By standardizing how outcomes are measur…