MS spasticity patterns linked to daily life struggles
NCT ID NCT07466823
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how muscle stiffness (spasticity) patterns in the arms and legs of people with multiple sclerosis relate to their quality of life. Researchers will classify these patterns and measure their impact using patient surveys and physical tests. The goal is to better understand spasticity to improve future treatments. About 75 adults with MS and spasticity will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients with multiple sclerosis and clinical spasticity will be recruited consecutively from the Multiple Sclerosis outpatient clinic of Marmara University Pendik Training and Research Hospital and from patients referred to the Physical Medicine and Rehabilitation outpatient clinic. Eligible participants will undergo clinical evaluation during a single study visit.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of multiple sclerosis according to the 2024 McDonald criteria * Age ≥ 18 years * Presence of clinical spasticity defined as Modified Ashworth Scale score ≥ 1 in at least one joint * Ability to understand study procedures and provide informed consent * Absence of significant cognitive impairment Exclusion Criteria: * Presence of orthopedic, rheumatologic, or neurological conditions affecting movement other than multiple sclerosis * Botulinum toxin type A injection within the previous 3 months * Previous surgical treatment for upper extremity spasticity * Bone deformities affecting the upper extremity * Inability or unwillingness to provide informed consent * Presence of cognitive impairment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854
RECRUITINGIstanbul, Turkey (Türkiye)
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